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atp4b.S ATPase H+/K+ transporting subunit beta S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379459, updated on 4-Nov-2024

Summary

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Official Symbol
atp4b.S
Official Full Name
ATPase H+/K+ transporting subunit beta S homeolog
Primary source
Xenbase:XB-GENE-944896
Locus tag
XELAEV_18015578mg
See related
EnsemblRapid:ENSXLAG00005031883 AllianceGenome:Xenbase:XB-GENE-944896
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
atp4b
Summary
Predicted to enable ATPase activator activity. Predicted to act upstream of or within intracellular monoatomic cation homeostasis and monoatomic cation transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of sodium:potassium-exchanging ATPase complex. Human ortholog(s) of this gene implicated in atrophic gastritis; autoimmune gastritis; and stomach cancer. Orthologous to human ATP4B (ATPase H+/K+ transporting subunit beta). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See atp4b.S in Genome Data Viewer
Location:
chromosome: 2S
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2S NC_054374.1 (106513725..106524869)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2S NC_030727.1 (97419077..97433268)

Chromosome 2S - NC_054374.1Genomic Context describing neighboring genes Neighboring gene cytokine receptor-like factor 2 Neighboring gene G protein-coupled receptor kinase 1 S homeolog Neighboring gene transcription factor Dp-1 S homeolog Neighboring gene DCN1, defective in cullin neddylation 1, domain containing 2 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC64342

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATPase activator activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within intracellular potassium ion homeostasis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within intracellular sodium ion homeostasis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within potassium ion import across plasma membrane IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within potassium ion transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within sodium ion export across plasma membrane IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within sodium ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
part_of sodium:potassium-exchanging ATPase complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ATPase H+/K+ transporting subunit beta S homeolog
Names
ATPase, H+/K+ exchanging, beta polypeptide S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086300.1 → NP_001079769.1  ATPase H+/K+ transporting subunit beta S homeolog

    See identical proteins and their annotated locations for NP_001079769.1

    Status: PROVISIONAL

    Source sequence(s)
    BC054193
    UniProtKB/TrEMBL
    A0A974DQ27, A0A974HWI7, O57527
    Related
    ENSXLAP00005095522.1, ENSXLAT00005097263.1
    Conserved Domains (1) summary
    cl08255
    Location:2 → 286
    Na_K-ATPase; Sodium / potassium ATPase beta chain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    106513725..106524869
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041582976.1 → XP_041438910.1  ATPase H+/K+ transporting subunit beta S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974DQ27, A0A974HWI7, O57527
    Conserved Domains (1) summary
    cl08255
    Location:2 → 286
    Na_K-ATPase; Sodium / potassium ATPase beta chain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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