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sparc.L secreted protein, acidic, cysteine-rich (osteonectin) L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379441, updated on 17-Aug-2024

Summary

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Official Symbol
sparc.L
Official Full Name
secreted protein, acidic, cysteine-rich (osteonectin) L homeolog
Primary source
Xenbase:XB-GENE-17342256
Locus tag
XELAEV_18016839mg
See related
EnsemblRapid:ENSXLAG00005022550
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
SPARC
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Genomic context

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Location:
chromosome: 3L
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (21900005..21918358, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (9510106..9528459)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene melatonin receptor type 1A likeL homeolog Neighboring gene FAT atypical cadherin 2 L homeolog Neighboring gene antioxidant 1 copper chaperone L homeolog Neighboring gene GTPase activating protein (SH3 domain) binding protein 1 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular analysis of Xenopus laevis SPARC (Secreted Protein, Acidic, Rich in Cysteine). A highly conserved acidic calcium-binding extracellular-matrix protein. Damjanovski S, et al. Biochem J, 1992 Jan 15. PMID 1736898, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC64258

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
SPARC
Names
BM-40
ON
basement-membrane protein 40
osteonectin
secreted protein acidic and rich in cysteine

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086283.1 → NP_001079752.1  SPARC precursor

    See identical proteins and their annotated locations for NP_001079752.1

    Status: PROVISIONAL

    Source sequence(s)
    BC054150
    UniProtKB/Swiss-Prot
    P36378
    UniProtKB/TrEMBL
    A0A974DAH7, Q7SZ40
    Related
    ENSXLAP00005066385.1, ENSXLAT00005067909.1
    Conserved Domains (3) summary
    cd00252
    Location:151 → 297
    SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
    cd01328
    Location:68 → 149
    FSL_SPARC; Follistatin-like SPARC (secreted protein, acidic, and rich in cysteines) domain; SPARC/BM-40/osteonectin is a multifunctional glycoprotein which modulates cellular interaction with the extracellular matrix by its binding to structural matrix proteins ...
    pfam10591
    Location:151 → 284
    SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    21900005..21918358 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P36378.1 GenPept UniProtKB/Swiss-Prot:P36378

Gene LinkOut

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Molecular Biology Databases
Research Materials