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frmd8.L FERM domain containing 8 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379363, updated on 4-Nov-2024

Summary

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Official Symbol
frmd8.L
Official Full Name
FERM domain containing 8 L homeolog
Primary source
Xenbase:XB-GENE-6079145
Locus tag
XELAEV_18022169mg
See related
EnsemblRapid:ENSXLAG00005021070 AllianceGenome:Xenbase:XB-GENE-6079145
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
frmd8
Summary
Predicted to act upstream of or within positive regulation of tumor necrosis factor production. Predicted to be located in cytosol and plasma membrane. Orthologous to human FRMD8 (FERM domain containing 8). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See frmd8.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (25039936..25065716, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (23492186..23517953, complement)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene SCY1-like, kinase-like 1 L homeolog Neighboring gene uncharacterized LOC121402969 Neighboring gene transfer RNA valine (anticodon UAC) Neighboring gene transfer RNA valine (anticodon UAC)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Kırlı K, et al. Elife, 2015 Dec 17. PMID 26673895, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC53754

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of tumor necrosis factor production ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
FERM domain-containing protein 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086207.1 → NP_001079676.1  FERM domain-containing protein 8

    See identical proteins and their annotated locations for NP_001079676.1

    Status: PROVISIONAL

    Source sequence(s)
    BC046857
    UniProtKB/Swiss-Prot
    Q7ZWP1
    UniProtKB/TrEMBL
    A0A974HNF3
    Related
    ENSXLAP00005061856.1, ENSXLAT00005063309.1
    Conserved Domains (2) summary
    smart00295
    Location:30 → 270
    B41; Band 4.1 homologues
    pfam00373
    Location:135 → 270
    FERM_M; FERM central domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    25039936..25065716 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7ZWP1.1 GenPept UniProtKB/Swiss-Prot:Q7ZWP1

Gene LinkOut

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