U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

tubb4a.S tubulin beta 4A class IVa S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379359, updated on 4-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
tubb4a.S
Official Full Name
tubulin beta 4A class IVa S homeolog
Primary source
Xenbase:XB-GENE-947413
Locus tag
XELAEV_18000833mg
See related
EnsemblRapid:ENSXLAG00005011467 AllianceGenome:Xenbase:XB-GENE-947413
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
tubb4; tubb5; tubb4a
Summary
Predicted to enable GTP binding activity and GTPase activity. Predicted to be a structural constituent of cytoskeleton. Predicted to act upstream of or within microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be located in cytoplasm and microtubule. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 6 and torsion dystonia 4. Orthologous to human TUBB4A (tubulin beta 4A class IVa). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See tubb4a.S in Genome Data Viewer
Location:
chromosome: 3S
Exon count:
4
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3S NC_054376.1 (126093844..126106234, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) Unplaced Scaffold NW_016694811.1 (2601093..2613488, complement)

Chromosome 3S - NC_054376.1Genomic Context describing neighboring genes Neighboring gene crumbs 3, cell polarity complex component S homeolog Neighboring gene uncharacterized LOC108703500 Neighboring gene A.superbus venom factor 1 Neighboring gene transfer RNA histidin (anticodon GUG)

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Protein interactomes of protein phosphatase 2A B55 regulatory subunits reveal B55-mediated regulation of replication protein A under replication stress. Wang F, et al. Sci Rep, 2018 Feb 8. PMID 29422626, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC53205

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within microtubule cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within microtubule-based process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
tubulin beta 4A class IVa S homeolog
Names
tubulin beta5
tubulin, beta 4
tubulin, beta 4A class IVa

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086203.1 → NP_001079672.1  tubulin beta 4A class IVa S homeolog

    See identical proteins and their annotated locations for NP_001079672.1

    Status: PROVISIONAL

    Source sequence(s)
    BC046853
    UniProtKB/TrEMBL
    Q66KS4, Q7ZWP4
    Related
    ENSXLAP00005033529.1, ENSXLAT00005034368.1
    Conserved Domains (2) summary
    PLN00220
    Location:1 → 430
    PLN00220; tubulin beta chain; Provisional
    cd02187
    Location:2 → 426
    beta_tubulin; The beta-tubulin family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054376.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    126093844..126106234 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.