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frrs1.S ferric-chelate reductase 1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379344, updated on 4-Nov-2024

Summary

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Official Symbol
frrs1.S
Official Full Name
ferric-chelate reductase 1 S homeolog
Primary source
Xenbase:XB-GENE-17340497
Locus tag
XELAEV_18025358mg
See related
EnsemblRapid:ENSXLAG00005009950 AllianceGenome:Xenbase:XB-GENE-17340497
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
fcr1
Summary
Predicted to enable oxidoreductase activity, acting on metal ions. Predicted to act upstream of or within intracellular iron ion homeostasis. Orthologous to human FRRS1 (ferric chelate reductase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See frrs1.S in Genome Data Viewer
Location:
chromosome: 4S
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4S NC_054378.1 (80943482..80961694)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4S NC_030731.1 (74748674..74762839)

Chromosome 4S - NC_054378.1Genomic Context describing neighboring genes Neighboring gene NPHS2 podocin S homeolog Neighboring gene sterol O-acyltransferase 1 S homeolog Neighboring gene uncharacterized LOC121393325 Neighboring gene palmdelphin S homeolog Neighboring gene calponin 3, acidic S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC53273

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables oxidoreductase activity, acting on metal ions IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within intracellular iron ion homeostasis IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ferric-chelate reductase 1 S homeolog
Names
Putative ferric-chelate reductase 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086188.1 → NP_001079657.1  ferric-chelate reductase 1 S homeolog precursor

    See identical proteins and their annotated locations for NP_001079657.1

    Status: PROVISIONAL

    Source sequence(s)
    BC046711
    UniProtKB/TrEMBL
    Q7ZWT9
    Conserved Domains (2) summary
    pfam02014
    Location:31 → 154
    Reeler; Reeler domain
    cl14783
    Location:190 → 251
    DOMON_like; Domon-like ligand-binding domains

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    80943482..80961694
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041591155.1 → XP_041447089.1  ferric-chelate reductase 1 S homeolog isoform X4

    UniProtKB/TrEMBL
    A0A1L8GG63, A0A974CZC5
    Related
    ENSXLAP00005029293.1, ENSXLAT00005030033.1
    Conserved Domains (2) summary
    pfam02014
    Location:31 → 154
    Reeler; Reeler domain
    cl14783
    Location:190 → 251
    DOMON_like; Domon-like ligand-binding domains

  2. XM_041591153.1 → XP_041447087.1  ferric-chelate reductase 1 S homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1MZ66
    Related
    ENSXLAP00005029320.1, ENSXLAT00005030060.1
    Conserved Domains (2) summary
    cd08544
    Location:45 → 177
    Reeler; the N-terminal domain of reelin, F-spondin, and a variety of other proteins
    cl14783
    Location:205 → 266
    DOMON_like; Domon-like ligand-binding domains

  3. XM_041591156.1 → XP_041447090.1  ferric-chelate reductase 1 S homeolog isoform X5

    UniProtKB/TrEMBL
    A0A8J1N1J3
    Conserved Domains (1) summary
    cd08544
    Location:45 → 177
    Reeler; the N-terminal domain of reelin, F-spondin, and a variety of other proteins

  4. XM_041591151.1 → XP_041447085.1  ferric-chelate reductase 1 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1N024
    Conserved Domains (2) summary
    cd08544
    Location:45 → 177
    Reeler; the N-terminal domain of reelin, F-spondin, and a variety of other proteins
    cl14783
    Location:205 → 266
    DOMON_like; Domon-like ligand-binding domains

  5. XM_041591152.1 → XP_041447086.1  ferric-chelate reductase 1 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1N024
    Related
    ENSXLAP00005029280.1, ENSXLAT00005030021.1
    Conserved Domains (2) summary
    cd08544
    Location:45 → 177
    Reeler; the N-terminal domain of reelin, F-spondin, and a variety of other proteins
    cl14783
    Location:205 → 266
    DOMON_like; Domon-like ligand-binding domains

  6. XM_041591154.1 → XP_041447088.1  ferric-chelate reductase 1 S homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J1N0S4
    Related
    ENSXLAP00005029300.1, ENSXLAT00005030040.1
    Conserved Domains (2) summary
    cd08544
    Location:31 → 163
    Reeler; the N-terminal domain of reelin, F-spondin, and a variety of other proteins
    cl14783
    Location:191 → 252
    DOMON_like; Domon-like ligand-binding domains

RNA

  1. XR_005967423.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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