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dnaja4.2.S DnaJ (Hsp40) homolog, subfamily A, member 4, gene 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379329, updated on 4-Nov-2024

Summary

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Official Symbol
dnaja4.2.S
Official Full Name
DnaJ (Hsp40) homolog, subfamily A, member 4, gene 2 S homeolog
Primary source
Xenbase:XB-GENE-5891700
Locus tag
XELAEV_18042774mg
See related
EnsemblRapid:ENSXLAG00005022173 AllianceGenome:Xenbase:XB-GENE-5891700
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
dnaja4; dnaja4.2; dnaja4.2.L
Summary
Predicted to enable several functions, including ATP binding activity; Hsp70 protein binding activity; and unfolded protein binding activity. Predicted to act upstream of or within protein refolding and response to heat. Predicted to be located in cytosol and membrane. Is expressed in nervous system; pharyngeal arch; vestibuloauditory system; and visual system. Orthologous to human DNAJA4 (DnaJ heat shock protein family (Hsp40) member A4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See dnaja4.2.S in Genome Data Viewer
Location:
chromosome: 8S
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8S NC_054386.1 (97759279..97771977, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8S NC_030739.1 (92732204..92744980, complement)

Chromosome 8S - NC_054386.1Genomic Context describing neighboring genes Neighboring gene interferon stimulated exonuclease gene 20kDa like 2 S homeolog Neighboring gene cellular retinoic acid binding protein 2 S homeolog Neighboring gene transfer RNA glycine (anticodon UCC) Neighboring gene nestin S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC52928

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables Hsp70 protein binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein-folding chaperone binding IEA
Inferred from Electronic Annotation
more info
  
enables unfolded protein binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein folding IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein refolding IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to heat IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DnaJ (Hsp40) homolog, subfamily A, member 4, gene 2 S homeolog
Names
DnaJ (Hsp40) homolog, subfamily A, member 4, gene 2 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086173.1 → NP_001079642.1  DnaJ (Hsp40) homolog, subfamily A, member 4, gene 2 S homeolog

    See identical proteins and their annotated locations for NP_001079642.1

    Status: PROVISIONAL

    Source sequence(s)
    BC046660
    UniProtKB/TrEMBL
    A0A974C4F6, Q7ZWX8
    Related
    ENSXLAP00005065286.1, ENSXLAT00005066802.1
    Conserved Domains (4) summary
    cd10719
    Location:139 → 205
    DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    cd10747
    Location:206 → 336
    DnaJ_C; C-terminal substrate binding domain of DnaJ and HSP40
    PTZ00037
    Location:2 → 399
    PTZ00037; DnaJ_C chaperone protein; Provisional
    pfam00226
    Location:7 → 65
    DnaJ; DnaJ domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    97759279..97771977 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials