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cyp2a6.S cytochrome P450 family 2 subfamily A member 6 gene 1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379297, updated on 4-Nov-2024

Summary

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Official Symbol
cyp2a6.S
Official Full Name
cytochrome P450 family 2 subfamily A member 6 gene 1 S homeolog
Primary source
Xenbase:XB-GENE-5820991
Locus tag
XELAEV_18042542mg
See related
EnsemblRapid:ENSXLAG00005008825 AllianceGenome:Xenbase:XB-GENE-5820991
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
cpc8; cyp2c8; cypiic8; cyp2c8.1; cyp2a6.1.S; mp-12/mp-20
Summary
Predicted to enable heme binding activity; iron ion binding activity; and monooxygenase activity. Predicted to act upstream of or within epoxygenase P450 pathway and xenobiotic metabolic process. Predicted to be located in cytoplasm; intracellular membrane-bounded organelle; and membrane. Orthologous to human CYP2A6 (cytochrome P450 family 2 subfamily A member 6). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cyp2a6.S in Genome Data Viewer
Location:
chromosome: 8S
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8S NC_054386.1 (84881458..84898359, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8S NC_030739.1 (82503503..82520344, complement)

Chromosome 8S - NC_054386.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450 family 2 subfamily A member 6 gene 11 S homeolog Neighboring gene cytochrome P450 family 2 subfamily a member 6 gene 2 S homeolog Neighboring gene AXL receptor tyrosine kinase S homeolog Neighboring gene olfactomedin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC54008

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables arachidonate epoxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within epoxygenase P450 pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within xenobiotic metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cytochrome P450 family 2 subfamily A member 6 gene 1 S homeolog
Names
cytochrome P450 family 2 subfamily A member 6 S homeolog
cytochrome P450, family 2, subfamily C, polypeptide 8, gene 1
NP_001079610.1
XP_041430005.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086141.1 → NP_001079610.1  cytochrome P450 family 2 subfamily A member 6 gene 1 S homeolog

    See identical proteins and their annotated locations for NP_001079610.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045126
    UniProtKB/TrEMBL
    A0A974C3W8, Q7ZX81
    Related
    ENSXLAP00005025632.1, ENSXLAT00005026344.1
    Conserved Domains (1) summary
    pfam00067
    Location:35 → 476
    p450; Cytochrome P450

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    84881458..84898359 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041574071.1 → XP_041430005.1  cytochrome P450 family 2 subfamily A member 6 gene 1 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1LMQ2
    Conserved Domains (1) summary
    cl12078
    Location:10 → 388
    p450; Cytochrome P450
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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