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eef1a1o.S eukaryotic translation elongation factor 1 alpha 1, oocyte form S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379289, updated on 4-Nov-2024

Summary

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Official Symbol
eef1a1o.S
Official Full Name
eukaryotic translation elongation factor 1 alpha 1, oocyte form S homeolog
Primary source
Xenbase:XB-GENE-17330483
Locus tag
XELAEV_18004064mg
See related
EnsemblRapid:ENSXLAG00005004870 AllianceGenome:Xenbase:XB-GENE-17330483
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
42Sp48; EF-1aO; xef1ao; eef1a-o1; EF-1-alpha-O; EF-1-ALPHA-O1
Summary
Predicted to enable GTP binding activity; GTPase activity; and translation elongation factor activity. Predicted to act upstream of or within translational elongation. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See eef1a1o.S in Genome Data Viewer
Location:
chromosome: 2S
Exon count:
7
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2S NC_054374.1 (82679654..82683857, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) Unplaced Scaffold NW_016694858.1 (607467..611673, complement)

Chromosome 2S - NC_054374.1Genomic Context describing neighboring genes Neighboring gene elongin A S homeolog Neighboring gene ribosomal protein L11 S homeolog Neighboring gene palmitoyl-protein thioesterase 1 S homeolog Neighboring gene cyclase associated actin cytoskeleton regulatory protein 1 S homeolog Neighboring gene major facilitator superfamily domain containing 2A S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolutionary importance of translation elongation factor eEF1A variant switching: eEF1A1 down-regulation in muscle is conserved in Xenopus but is controlled at a post-transcriptional level. Newbery HJ, et al. Biochem Biophys Res Commun, 2011 Jul 22. PMID 21722626
  2. Isolation and characterization of the gene encoding EF-1 alpha O, an elongation factor 1-alpha expressed during early development of Xenopus laevis. Frydenberg J, et al. Gene, 1991 Dec 30. PMID 1765266
  3. Three genes under different developmental control encode elongation factor 1-alpha in Xenopus laevis. Djé MK, et al. Nucleic Acids Res, 1990 Jun 25. PMID 2362804, Free PMC Article
  4. 42Sp48 in previtellogenic Xenopus oocytes is structurally homologous to EF-1 alpha and may be a stage-specific elongation factor. Coppard NJ, et al. J Cell Biol, 1991 Jan. PMID 1988459, Free PMC Article
  5. Two forms of elongation factor 1 alpha (EF-1 alpha O and 42Sp50), present in oocytes, but absent in somatic cells of Xenopus laevis. Deschamps S, et al. J Cell Biol, 1991 Sep. PMID 1894690, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. isoform switching in Xenopus laevis may have evolved because of a need for certain cell types to modify the well-established non-canonical functions of eEF1A1.
    Title: Evolutionary importance of translation elongation factor eEF1A variant switching: eEF1A1 down-regulation in muscle is conserved in Xenopus but is controlled at a post-transcriptional level.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC53846

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables translation elongation factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within translational elongation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
elongation factor 1-alpha, oocyte form
Names
EF-1AO1
elongation factor 1 alpha, oocyte form
elongation factor Tu

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086133.1 → NP_001079602.1  elongation factor 1-alpha, oocyte form

    See identical proteins and their annotated locations for NP_001079602.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045083
    UniProtKB/Swiss-Prot
    P17508
    UniProtKB/TrEMBL
    A0A8J0PNX7, A0A974BSC7, A0AA97PZ01, Q7ZXA2
    Related
    ENSXLAP00005014532.1, ENSXLAT00005014728.1
    Conserved Domains (4) summary
    PTZ00141
    Location:1 → 461
    PTZ00141; elongation factor 1- alpha; Provisional
    cd01883
    Location:9 → 239
    EF1_alpha; Elongation Factor 1-alpha (EF1-alpha) protein family
    cd03693
    Location:242 → 332
    EF1_alpha_II; Domain II of elongation factor 1-alpha
    cd03705
    Location:335 → 438
    EF1_alpha_III; Domain III of Elongation Factor 1

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    82679654..82683857 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P17508.2 GenPept UniProtKB/Swiss-Prot:P17508

Gene LinkOut

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