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dstn.S destrin, actin depolymerizing factor S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379282, updated on 4-Nov-2024

Summary

Official Symbol
dstn.S
Official Full Name
destrin, actin depolymerizing factor S homeolog
Primary source
Xenbase:XB-GENE-6077624
Locus tag
XELAEV_18028899mg
See related
EnsemblRapid:ENSXLAG00005007679 AllianceGenome:Xenbase:XB-GENE-6077624
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ADF; dstn; actdp; destrin
Summary
Predicted to enable actin filament binding activity. Predicted to act upstream of or within actin filament fragmentation and actin filament severing. Predicted to be located in several cellular components, including actin cytoskeleton; cytoplasm; and nucleus. Orthologous to human DSTN (destrin, actin depolymerizing factor). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See dstn.S in Genome Data Viewer
Location:
chromosome: 5S
Exon count:
4
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5S NC_054380.1 (31395692..31414228)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5S NC_030733.1 (31472760..31491330)

Chromosome 5S - NC_054380.1Genomic Context describing neighboring genes Neighboring gene cystatin-C Neighboring gene cystatin Neighboring gene BCL2 like 11 S homeolog Neighboring gene uncharacterized LOC108717790 Neighboring gene two pore calcium channel protein 1

Genomic regions, transcripts, and products

General gene information

Clone Names

  • MGC53245

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within actin filament depolymerization IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within actin filament fragmentation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within actin filament severing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
destrin, actin depolymerizing factor S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086126.1NP_001079595.1  destrin, actin depolymerizing factor S homeolog

    See identical proteins and their annotated locations for NP_001079595.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045044
    UniProtKB/TrEMBL
    A0A974CR90, Q7ZXD4
    Related
    ENSXLAP00005021842.1, ENSXLAT00005022533.1
    Conserved Domains (1) summary
    cd11286
    Location:3140
    ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054380.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    31395692..31414228
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)