U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

cbfa2t2.L CBFA2/RUNX1 translocation partner 2 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379213, updated on 7-Sep-2023

Summary

Go to the top of the page Help
Official Symbol
cbfa2t2.L
Official Full Name
CBFA2/RUNX1 translocation partner 2 L homeolog
Primary source
Xenbase:XB-GENE-950038
Locus tag
XELAEV_18043980mg
See related
EnsemblRapid:ENSXLAG00005023186
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
MTGR1; XETOR; cbfa2t2; cbfa2t2-a
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See cbfa2t2.L in Genome Data Viewer
Location:
chromosome: 9_10L
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (45255805..45281233)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (34934381..34959921)

Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene traf2 and NCK-interacting protein kinase-like Neighboring gene phosphatidylinositol glycan anchor biosynthesis class T L homeolog Neighboring gene interleukin-17D Neighboring gene N-terminal EF-hand calcium binding protein 3 L homeolog

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. XETOR regulates the size of the proneural domain during primary neurogenesis in Xenopus laevis. Cao Y, et al. Mech Dev, 2002 Nov. PMID 12385752
  2. The expression and function of MTG/ETO family proteins during neurogenesis. Koyano-Nakagawa N, et al. Dev Biol, 2005 Feb 1. PMID 15649458
  3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC53378

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of DNA-templated transcription IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within negative regulation of neurogenesis IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within negative regulation of neuron projection development ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
protein CBFA2T2
Names
MTG8-like protein
MTG8-related protein 1
a subunit 2; translocated to, 2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2 L homeolog
expressed during neurogenesis

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086057.1 → NP_001079526.1  protein CBFA2T2

    See identical proteins and their annotated locations for NP_001079526.1

    Status: PROVISIONAL

    Source sequence(s)
    BC044006
    UniProtKB/TrEMBL
    Q5IJ69, Q7ZY26
    Related
    ENSXLAP00005068650.1, ENSXLAT00005070184.1
    Conserved Domains (4) summary
    pfam01753
    Location:497 → 533
    zf-MYND; MYND finger
    pfam07531
    Location:104 → 190
    TAFH; NHR1 homology to TAF
    pfam08788
    Location:322 → 388
    NHR2; NHR2 domain like
    cl23750
    Location:423 → 478
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    45255805..45281233
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041575479.1 → XP_041431413.1  protein CBFA2T2 isoform X2

    UniProtKB/TrEMBL
    A0A8J1LPB5, A0A974BXW6, Q5IJ69
    Related
    ENSXLAP00005068728.1, ENSXLAT00005070262.1
    Conserved Domains (3) summary
    smart00549
    Location:56 → 146
    TAFH; TAF homology
    COG1390
    Location:375 → 448
    NtpE; Archaeal/vacuolar-type H+-ATPase subunit E/Vma4 [Energy production and conversion]
    pfam08788
    Location:274 → 340
    NHR2; NHR2 domain like

  2. XM_041575478.1 → XP_041431412.1  protein CBFA2T2 isoform X1

    UniProtKB/TrEMBL
    A0A8J1LPE2, A0A974BXW6
    Related
    ENSXLAP00005068690.1, ENSXLAT00005070224.1
    Conserved Domains (3) summary
    smart00549
    Location:120 → 210
    TAFH; TAF homology
    COG1390
    Location:439 → 512
    NtpE; Archaeal/vacuolar-type H+-ATPase subunit E/Vma4 [Energy production and conversion]
    pfam08788
    Location:338 → 404
    NHR2; NHR2 domain like
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9IAB2.2 GenPept UniProtKB/Swiss-Prot:Q9IAB2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.