esrp1.L epithelial splicing regulatory protein 1 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: esrp1.L
Official Full Name: epithelial splicing regulatory protein 1 L homeolog
Primary source: Xenbase:XB-GENE-985143
Locus tag: XELAEV_18032204mg
See related: EnsemblRapid:ENSXLAG00005032763
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: esrp1; rbm35a
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Genomic context

Location:: chromosome: 6L

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	6L	NC_054381.1 (137999119..138051303)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	6L	NC_030734.1 (128805994..128857363)

Chromosome 6L - NC_054381.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Ptbp1 abundance is controlled in Xenopus epidermis via alternate splicing: skipping of exon 11 is the default splicing pattern, but Esrp1 stimulates ptbp1 expression by favoring the inclusion of exon 11 up to a level that is limited by Ptbp1 itself.
Title: A posttranscriptional mechanism that controls Ptbp1 abundance in the Xenopus epidermis.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables mRNA binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA splicing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mRNA processing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of RNA splicing	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: epithelial splicing regulatory protein 1

Names: RNA-binding motif protein 35A; RNA-binding protein 35A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001086055.1 → NP_001079524.1 epithelial splicing regulatory protein 1

See identical proteins and their annotated locations for NP_001079524.1

Status: PROVISIONAL

Source sequence(s)

BC044002

UniProtKB/Swiss-Prot

Q7ZY29

UniProtKB/TrEMBL

A0A974CQN4

Related

ENSXLAP00005098195.1, ENSXLAT00005100002.1

Conserved Domains (6) summary

COG0724
Location:286 → 398

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

cd12736
Location:222 → 306

RRM1_ESRP1; RNA recognition motif 1 in epithelial splicing regulatory protein 1 (ESRP1) and similar proteins

cd12739
Location:311 → 419

RRM2_ESRP1; RNA recognition motif 2 in epithelial splicing regulatory protein 1 (ESRP1) and similar proteins

cd12742
Location:445 → 525

RRM3_ESRP1_ESRP2; RNA recognition motif in epithelial splicing regulatory protein ESRP1, ESRP2 and similar proteins

cl10012
Location:8 → 146

DnaQ_like_exo; DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily

cl17169
Location:639 → 676

RRM_SF; RNA recognition motif (RRM) superfamily

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

137999119..138051303

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_018266214.2 → XP_018121703.1 epithelial splicing regulatory protein 1 isoform X2

UniProtKB/TrEMBL

A0A8J0VH46, A0A974CQN4
XM_018266213.2 → XP_018121702.1 epithelial splicing regulatory protein 1 isoform X1

UniProtKB/TrEMBL

A0A8J0VMF6, A0A974CQN4