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capn13.L calpain 13 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379175, updated on 4-Nov-2024

Summary

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Official Symbol
capn13.L
Official Full Name
calpain 13 L homeolog
Primary source
Xenbase:XB-GENE-6045553
Locus tag
XELAEV_18026315mg
See related
EnsemblRapid:ENSXLAG00005034402 AllianceGenome:Xenbase:XB-GENE-6045553
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
capn11; capn13
Summary
Predicted to enable calcium ion binding activity and calcium-dependent cysteine-type endopeptidase activity. Predicted to act upstream of or within proteolysis. Predicted to be located in cytoplasm. Orthologous to human CAPN13 (calpain 13). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See capn13.L in Genome Data Viewer
Location:
chromosome: 5L
Exon count:
26
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5L NC_054379.1 (19101596..19157260)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5L NC_030732.1 (18418760..18474482)

Chromosome 5L - NC_054379.1Genomic Context describing neighboring genes Neighboring gene polypeptide N-acetylgalactosaminyltransferase 14 L homeolog Neighboring gene calpain 10-like L homeolog Neighboring gene lysocardiolipin acyltransferase 1 L homeolog Neighboring gene uncharacterized LOC121393607

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC53127

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables cysteine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
calpain 13 L homeolog
Names
calpain 11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086019.1 → NP_001079488.1  calpain 13 L homeolog

    See identical proteins and their annotated locations for NP_001079488.1

    Status: PROVISIONAL

    Source sequence(s)
    BC043810
    UniProtKB/TrEMBL
    A0A974HIW8, Q7ZYF3
    Related
    ENSXLAP00005103078.1, ENSXLAT00005105082.1
    Conserved Domains (3) summary
    cd00051
    Location:639 → 685
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00648
    Location:48 → 341
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:356 → 497
    Calpain_III; Calpain large subunit, domain III

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    19101596..19157260
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041562066.1 → XP_041418000.1  calpain 13 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1KL07, A0A974HIW8
    Conserved Domains (3) summary
    cd16195
    Location:593 → 762
    EFh_PEF_CAPN13_14; Penta-EF hand, calcium binding motifs, found in calpain-13 (CAPN13), calpain-14 (CAPN14), and similar proteins
    pfam00648
    Location:48 → 341
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:364 → 493
    Calpain_III; Calpain large subunit, domain III

  2. XM_041562065.1 → XP_041417999.1  calpain 13 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1KL07, A0A974HIW8
    Conserved Domains (3) summary
    cd16195
    Location:593 → 762
    EFh_PEF_CAPN13_14; Penta-EF hand, calcium binding motifs, found in calpain-13 (CAPN13), calpain-14 (CAPN14), and similar proteins
    pfam00648
    Location:48 → 341
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:364 → 493
    Calpain_III; Calpain large subunit, domain III
Nucleotide Protein Strain
Heading Accession and Version

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