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rab32a RAB32a, member RAS oncogene family [ Danio rerio (zebrafish) ]

Gene ID: 378969, updated on 12-Sep-2024

Summary

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Official Symbol
rab32aprovided by ZNC
Official Full Name
RAB32a, member RAS oncogene familyprovided by ZNC
Primary source
ZFIN:ZDB-GENE-031006-10
See related
Ensembl:ENSDARG00000029036 AllianceGenome:ZFIN:ZDB-GENE-031006-10
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb914; rab32; zgc:110481; hm:zehn1770
Summary
Predicted to enable GTPase activity. Acts upstream of or within notochord cell vacuolation. Predicted to be located in Golgi apparatus; membrane; and vesicle. Predicted to be active in melanosome; mitochondrion; and trans-Golgi network. Is expressed in several structures, including Kupffer's vesicle; axial mesoderm; neural crest; retinal pigmented epithelium; and shield. Orthologous to human RAB32 (RAB32, member RAS oncogene family). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See rab32a in Genome Data Viewer
Location:
chromosome: 20
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (32009270..32045005, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (32106391..32142126, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene syntaxin binding protein 5a (tomosyn) Neighboring gene androglobin Neighboring gene glutamate receptor, metabotropic 1a Neighboring gene CD164 molecule, sialomucin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Notochord vacuoles absorb compressive bone growth during zebrafish spine formation. Bagwell J, et al. Elife, 2020 Jan 29. PMID 31995030, Free PMC Article
  2. Tissue self-organization underlies morphogenesis of the notochord. Norman J, et al. Philos Trans R Soc Lond B Biol Sci, 2018 Sep 24. PMID 30249771, Free PMC Article
  3. Sheath Cell Invasion and Trans-differentiation Repair Mechanical Damage Caused by Loss of Caveolae in the Zebrafish Notochord. Garcia J, et al. Curr Biol, 2017 Jul 10. PMID 28648824, Free PMC Article
  4. prdm1a Regulates sox10 and islet1 in the development of neural crest and Rohon-Beard sensory neurons. Olesnicky E, et al. Genesis, 2010 Nov. PMID 20836130, Free PMC Article
  5. Lysosome-Rich Enterocytes Mediate Protein Absorption in the Vertebrate Gut. Park J, et al. Dev Cell, 2019 Oct 7. PMID 31474562, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in melanosome organization IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within notochord cell vacuolation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in melanosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in trans-Golgi network IEA
Inferred from Electronic Annotation
more info
  
located_in vesicle IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ras-related protein Rab-32a
Names
RAB32, member RAS oncogene family

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201332.1 → NP_958489.1  ras-related protein Rab-32a

    See identical proteins and their annotated locations for NP_958489.1

    Status: PROVISIONAL

    Source sequence(s)
    BC049531
    UniProtKB/TrEMBL
    Q7ZW88
    Related
    ENSDARP00000032828.3, ENSDART00000034248.6
    Conserved Domains (2) summary
    smart00175
    Location:14 → 183
    RAB; Rab subfamily of small GTPases
    cd04107
    Location:14 → 213
    Rab32_Rab38; Rab GTPase families 18 (Rab18) and 32 (Rab32)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    32009270..32045005 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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