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SerT - Serotonin transporter

Enables serotonin:sodium:chloride symporter activity. Involved in serotonin uptake. Located in axon terminus. Is expressed in several structures, including adult brain; anterior-posterior subdivision of organism; ganglia; serotonergic neurons; and synaptic neuropil domain. Used to study generalized anxiety disorder. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; anxiety disorder (multiple); depressive disorder (multiple); heart disease (multiple); and substance abuse (multiple). Orthologous to human SLC6A4 (solute carrier family 6 member 4). [provided by Alliance of Genome Resources, Oct 2024]

Genes similar to SerT

NCBI Orthologs

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Species Gene Architecture aa