BRS3 bombesin receptor subtype 3 [Gallus gallus (chicken)] - Gene

Summary

Symbol: BRS3provided by CGNC
Full Name: bombesin receptor subtype 3provided by CGNC
Primary source: CGNC:4824
See related: Ensembl:ENSGALG00010014519
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	4	NC_052535.1 (4278246..4287516)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	4	NC_052576.1 (4313772..4323041)

Chromosome 4 - NC_052535.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Structural and functional characterization of GRP, neuromedulin B, NMBR, and BRS3 in chickens has been reported.
Title: Characterization of NMB, GRP and their receptors (BRS3, NMBR and GRPR) in chickens.
Gastrin-releasing peptide receptor[chGRP-R] and chBRS-3.5 mRNA occurred in brain regions similar to those of mammals that express GRP-R. BN/GRP-immunoreactive neurons were found mainly in the pallium, a distribution like that of chBRS-3.5 mRNA
Title: Distributions of two chicken bombesin receptors, bombesin receptor subtype-3.5 (chBRS-3.5) and gastrin-releasing peptide receptor (chGRP-R) mRNAS in the chicken telencephalon.
Expression of BRS-3.5 receptor is detected in chick brain; when expressed in Chinese hamster ovary K1 cells, chick BRS-3.5 receptor mediates intracellular calcium mobilization upon agonist stimulation.
Title: Molecular cloning and characterization of avian bombesin-like peptide receptors: new tools for investigating molecular basis for ligand selectivity.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables bombesin receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in bombesin receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: bombesin receptor subtype-3

Names: bombesin-like peptide receptor subtype 3.5; bombesin-like receptor 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.