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TNFRSF11B TNF receptor superfamily member 11b [ Gallus gallus (chicken) ]

Gene ID: 378803, updated on 10-Oct-2024

Summary

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Symbol
TNFRSF11Bprovided by CGNC
Full Name
TNF receptor superfamily member 11bprovided by CGNC
Primary source
CGNC:12044
See related
Ensembl:ENSGALG00010009219
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
OPG
Orthologs
human mouse all
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Genomic context

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See TNFRSF11B in Genome Data Viewer
Location:
chromosome: 2
Exon count:
5
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (135324723..135342421, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (135532760..135550446, complement)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121109905 Neighboring gene uncharacterized LOC121109906 Neighboring gene collectin subfamily member 10 Neighboring gene mal, T-cell differentiation protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Effects of manganese deficiency on the microstructure of proximal tibia and OPG/RANKL gene expression in chicks. Liu R, et al. Vet Res Commun, 2015 Mar. PMID 25634035
  2. Characterization of chicken TNFR superfamily decoy receptors, DcR3 and osteoprotegerin. Bridgham JT, et al. Biochem Biophys Res Commun, 2003 Aug 8. PMID 12878204
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tumor necrosis factor receptor superfamily member 11B
Names
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033641.2 → NP_001028813.2  tumor necrosis factor receptor superfamily member 11B precursor

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000044
    UniProtKB/TrEMBL
    A0A8V0Y2R7, Q4F9K2
    Related
    ENSGALP00010012607.1, ENSGALT00010021999.1
    Conserved Domains (4) summary
    smart00005
    Location:289 → 354
    DEATH; DEATH domain, found in proteins involved in cell death (apoptosis)
    cd01670
    Location:223 → 291
    Death; Death Domain: a protein-protein interaction domain
    cd00185
    Location:124 → 186
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)
    cd10581
    Location:6 → 152
    TNFRSF11B; Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B), also known as Osteoprotegerin (OPG)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    135324723..135342421 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015283019.4 → XP_015138505.1  tumor necrosis factor receptor superfamily member 11B isoform X1

    UniProtKB/TrEMBL
    A0A3Q2U211, A0A8V0Y2R3
    Related
    ENSGALP00010012615.1, ENSGALT00010022009.1
    Conserved Domains (3) summary
    cd00185
    Location:85 → 147
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)
    pfam00531
    Location:251 → 327
    Death; Death domain
    cl22855
    Location:1 → 113
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    135532760..135550446 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046910215.1 → XP_046766171.1  tumor necrosis factor receptor superfamily member 11B isoform X1

    UniProtKB/TrEMBL
    A0A3Q2U211
Nucleotide Protein Strain
Heading Accession and Version

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