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CG3356 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37876, updated on 2-Nov-2024

Summary

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Official Symbol
CG3356provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0034989
Locus tag
Dmel_CG3356
See related
AllianceGenome:FB:FBgn0034989
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG3356
Summary
Enables ubiquitin conjugating enzyme binding activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Is expressed in adult head and organism. Orthologous to human UBE3C (ubiquitin protein ligase E3C). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See CG3356 in Genome Data Viewer
Location:
60C2-60C2; 2-106 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24197824..24202187)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20085347..20089710)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene over compensating males Neighboring gene cytosolic 5'-nucleotidase IIIB Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44827

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. UbcD4, a ubiquitin-conjugating enzyme in Drosophila melanogaster expressed in pole cells. Canning M, et al. Mol Genet Genomics, 2002 Feb. PMID 11862484
  2. Identification and characterization of a Drosophila proteasome regulatory network. Lundgren J, et al. Mol Cell Biol, 2005 Jun. PMID 15899868, Free PMC Article
  3. Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster. Ni JQ, et al. Nat Methods, 2008 Jan. PMID 18084299, Free PMC Article
  4. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article
  5. Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. Blanco E, et al. BMC Dev Biol, 2010 Sep 2. PMID 20813047, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ubiquitin conjugating enzyme binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin protein ligase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables ubiquitin-protein transferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in protein polyubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein polyubiquitination IEA
Inferred from Electronic Annotation
more info
  
involved_in protein polyubiquitination ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG3356-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    24197824..24202187
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_138052.3 → NP_611896.1  uncharacterized protein Dmel_CG3356 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611896.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W196
    Related
    FBpp0072169
    Conserved Domains (2) summary
    smart00119
    Location:788 → 1119
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd00078
    Location:766 → 1120
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W196 Q9W196

Gene LinkOut

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