pck1 - phosphoenolpyruvate carboxykinase 1 (soluble)
Predicted to enable manganese ion binding activity and phosphoenolpyruvate carboxykinase (GTP) activity. Acts upstream of or within monoatomic ion homeostasis and response to glucose. Predicted to be active in cytosol. Is expressed in several structures, including alar plate midbrain region; digestive system; midbrain; musculature system; and visceral fat. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Orthologous to human PCK1 (phosphoenolpyruvate carboxykinase 1). [provided by Alliance of Genome Resources, Oct 2024]
NCBI Orthologs
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Protein alignment
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