cck.S cholecystokinin S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: cck.S
Official Full Name: cholecystokinin S homeolog
Primary source: Xenbase:XB-GENE-6252398
Locus tag: XELAEV_18033214mg
See related: EnsemblRapid:ENSXLAG00005019839 AllianceGenome:Xenbase:XB-GENE-6252398
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: cck; cck-a; cck-b; CCK-CG; CCK-CH
Summary: Predicted to enable neuropeptide hormone activity. Predicted to act upstream of or within digestion. Predicted to be located in axon and extracellular space. Human ortholog(s) of this gene implicated in alcohol dependence and nicotine dependence. Orthologous to human CCK (cholecystokinin). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 6S

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	6S	NC_054382.1 (46869461..46876895, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	6S	NC_030735.1 (45605472..45612906, complement)

Chromosome 6S - NC_054382.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables hormone activity	IEA Inferred from Electronic Annotation more info
enables neuropeptide hormone activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within digestion	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in axon	IEA Inferred from Electronic Annotation more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in extracellular space	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cholecystokinin A

Names: cholecystokinin (clone CCK-CG), preprocholecystokinin; cholecystokinin type 1; preprocholecystokinin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001085834.1 → NP_001079303.1 cholecystokinin A preproprotein

See identical proteins and their annotated locations for NP_001079303.1

Status: VALIDATED

Source sequence(s)

Z47557

UniProtKB/Swiss-Prot

B7ZQP7, P50144

UniProtKB/TrEMBL

A0A974CKE0

Related

ENSXLAP00005058258.1, ENSXLAT00005059615.1

Conserved Domains (1) summary

pfam00918
Location:4 → 123

Gastrin; Gastrin/cholecystokinin family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054382.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

46869461..46876895 complement

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GenBank, FASTA, Sequence Viewer (Graphics)