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Gm10033 predicted gene 10033 [ Mus musculus (house mouse) ]

Gene ID: 378466, updated on 2-Nov-2024

Summary

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Official Symbol
Gm10033provided by MGI
Official Full Name
predicted gene 10033provided by MGI
Primary source
MGI:MGI:3642803
See related
Ensembl:ENSMUSG00000110444 AllianceGenome:MGI:3642803
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm10311; 9330175B10Rik; E230024E03Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in cerebellum adult (RPKM 1.7), bladder adult (RPKM 1.4) and 21 other tissues See more
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Genomic context

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See Gm10033 in Genome Data Viewer
Location:
8 B3.3; 8
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (69821180..69848196, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (69368528..69395544, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E2263 Neighboring gene STARR-seq mESC enhancer starr_21728 Neighboring gene zinc finger protein 781A Neighboring gene STARR-seq mESC enhancer starr_21730 Neighboring gene STARR-positive B cell enhancer mm9_chr8:71852567-71852867 Neighboring gene eukaryotic translation initiation factor 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_21735 Neighboring gene POTE ankyrin domain family member 3C Neighboring gene STARR-positive B cell enhancer mm9_chr8:71994362-71994663 Neighboring gene POTE ankyrin domain family member 3D

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC378466

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001374599.1 → NP_001361528.1  uncharacterized protein LOC378466 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC117621, AC162797
    UniProtKB/TrEMBL
    A0A6I8MX06
    Related
    ENSMUSP00000159337.2, ENSMUST00000239456.2
    Conserved Domains (3) summary
    COG5048
    Location:469 → 845
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:529 → 549
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:40 → 80
    KRAB; KRAB box

  2. NM_001374600.1 → NP_001361529.1  uncharacterized protein LOC378466 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC117621, AC162797
    UniProtKB/TrEMBL
    A0A6I8MX21
    Related
    ENSMUSP00000159375.2, ENSMUST00000072427.7
    Conserved Domains (3) summary
    COG5048
    Location:433 → 809
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:493 → 513
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:4 → 44
    KRAB; KRAB box

RNA

  1. NR_038043.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) is the longer transcript with multiple exons.
    Source sequence(s)
    AC117621, AC162797

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    69821180..69848196 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_194351.1: Suppressed sequence

    Description
    NM_194351.1: This RefSeq was permanently suppressed because it is now thought that this gene does not encode a protein.

  2. NR_038044.1: Suppressed sequence

    Description
    NR_038044.1: This RefSeq was removed because currently there is not sufficient data to support this transcript.
Nucleotide Protein Strain
Heading Accession and Version

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