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PHDP - Putative homeodomain protein

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in embryonic brain and larval ventral nerve cord. Human ortholog(s) of this gene implicated in colorectal cancer; congenital central hypoventilation syndrome; congenital fibrosis of the extraocular muscles 2; and neuroblastoma. Orthologous to several human genes including PHOX2B (paired like homeobox 2B). [provided by Alliance of Genome Resources, Oct 2024]

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Species Gene Architecture aa