Pym Partner of Y14 and Mago [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Pymprovided by FlyBase
Official Full Name: Partner of Y14 and Magoprovided by FlyBase
Primary source: FLYBASE:FBgn0034918
Locus tag: Dmel_CG30176
See related: AllianceGenome:FB:FBgn0034918
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BEST:HL05757; CG10330; CG30176; Dmel\CG30176; pym; PYM; UD3; wibg; Wibg
Summary: Enables RNA binding activity and exon-exon junction complex binding activity. Involved in exon-exon junction complex disassembly. Located in cytoplasm. Part of exon-exon junction complex. Is expressed in follicle cell; germarium; nurse cell; oocyte; and organism. Orthologous to human PYM1 (PYM homolog 1, exon junction complex associated factor). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (23855954..23856936, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (19743477..19744459, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA binding	IDA Inferred from Direct Assay more info	PubMed
NOT enables eukaryotic initiation factor 4E binding	IPI Inferred from Physical Interaction more info	PubMed
NOT enables eukaryotic initiation factor 4G binding	IPI Inferred from Physical Interaction more info	PubMed
enables exon-exon junction complex binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
NOT enables ribosomal small subunit binding	IDA Inferred from Direct Assay more info	PubMed
NOT enables ribosomal small subunit binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
NOT involved_in cap-dependent translational initiation	IPI Inferred from Physical Interaction more info	PubMed
involved_in exon-exon junction complex disassembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in exon-exon junction complex disassembly	IEA Inferred from Electronic Annotation more info
involved_in exon-exon junction complex disassembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
part_of exon-exon junction complex	IBA Inferred from Biological aspect of Ancestor more info
part_of exon-exon junction complex	IDA Inferred from Direct Assay more info	PubMed