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mRpL43 mitochondrial ribosomal protein L43 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37750, updated on 2-Nov-2024

Summary

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Official Symbol
mRpL43provided by FlyBase
Official Full Name
mitochondrial ribosomal protein L43provided by FlyBase
Primary source
FLYBASE:FBgn0034893
Locus tag
Dmel_CG5479
See related
AllianceGenome:FB:FBgn0034893
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RE35686; CG5479; CI-B8; Dmel\CG5479; mRpL-CI-B8; mRPL43
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be part of mitochondrial large ribosomal subunit. Is expressed in several structures, including adult heart; dorsal pharyngeal muscle cell; embryonic anal pad; embryonic/larval midgut primordium; and gut section. Orthologous to human MRPL43 (mitochondrial ribosomal protein L43). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

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See mRpL43 in Genome Data Viewer
Location:
59F6-59F6; 2-104 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23698105..23699014)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19585628..19586537)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Peptidyl-alpha-hydroxyglycine-alpha-amidating lyase 2 Neighboring gene uncharacterized protein Neighboring gene angel Neighboring gene salivary glands marred Neighboring gene lethal-(2)-denticleless Neighboring gene ALG3, alpha-1,3- mannosyltransferase Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Natural variation in sugar tolerance associates with changes in signaling and mitochondrial ribosome biogenesis. Melvin RG, et al. Elife, 2018 Nov 27. PMID 30480548, Free PMC Article
  2. Extensive translation of small Open Reading Frames revealed by Poly-Ribo-Seq. Aspden JL, et al. Elife, 2014 Aug 21. PMID 25144939, Free PMC Article
  3. Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. Suzuki T, et al. J Biol Chem, 2001 Jun 15. PMID 11279069
  4. The mitochondrial outer membrane protein MDI promotes local protein synthesis and mtDNA replication. Zhang Y, et al. EMBO J, 2016 May 17. PMID 27053724, Free PMC Article
  5. Discovery and Visualization of Age-Dependent Patterns in the Diurnal Transcriptome of Drosophila. Sebastian B, et al. J Circadian Rhythms, 2022. PMID 36561348, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial translation IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial translation TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial large ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of mitochondrial large ribosomal subunit TAS
Traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
mitochondrial ribosomal protein L43
Names
CG5479-PA
mRpL43-PA
mitochondrial ribosomal protein L-CI-B8

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    23698105..23699014
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079104.3 → NP_523828.1  mitochondrial ribosomal protein L43 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523828.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W1L1
    Related
    FBpp0071993
    Conserved Domains (1) summary
    smart00916
    Location:40 → 109
    L51_S25_CI-B8; Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W1L1 Q9W1L1

Gene LinkOut

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