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Snapin SNAP associated protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3772677, updated on 18-Sep-2024

Summary

Official Symbol
Snapinprovided by FlyBase
Official Full Name
SNAP associated proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031455
Locus tag
Dmel_CG9958
See related
AllianceGenome:FB:FBgn0031455
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG32951; CG9958; Dmel\CG9958; Dromel_CG9960_CG9958_FBtr007773_snapin_uORF; NP_722835; snapin; SNAPIN
Summary
Predicted to enable SNARE binding activity. Involved in autophagosome-lysosome fusion and homeostatic process. Located in synaptic vesicle. Orthologous to human SNAPIN (SNAP associated protein). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See Snapin in Genome Data Viewer
Location:
23A3-23A3; 2-7 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2758427..2759677, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2758427..2759677, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Cwc25 Neighboring gene Phosphoglycerate kinase Neighboring gene Bacchus Neighboring gene long non-coding RNA:CR44772 Neighboring gene HemK methyltransferase 2 Neighboring gene Transportin-Serine/Arginine rich Neighboring gene Sorting nexin 21 Neighboring gene anterior pharynx defective 1

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in autophagosome-lysosome fusion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in endosome to lysosome transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in homeostatic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in lysosome localization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in lysosome organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in neurotransmitter secretion NAS
Non-traceable Author Statement
more info
PubMed 
involved_in synaptic vesicle exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in synaptic vesicle exocytosis ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in synaptic vesicle priming NAS
Non-traceable Author Statement
more info
PubMed 
involved_in synaptic vesicle transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of BLOC-1 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of BLOC-1 complex IEA
Inferred from Electronic Annotation
more info
 
part_of BLOC-1 complex ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
is_active_in secretory granule IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in synaptic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in synaptic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in synaptic vesicle NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
SNAP associated protein
Names
CG9958-PA
CPuORF of FBgn0031454
Snapin-PA
snapin
snapin ortholog

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    2758427..2759677 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_164499.2NP_722835.1  SNAP associated protein [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722835.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VQF9
    UniProtKB/TrEMBL
    N0BKF4
    Conserved Domains (1) summary
    pfam14712
    Location:25111
    Snapin_Pallidin; Snapin/Pallidin