Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search NCBI

Egfr - Epidermal growth factor receptor

Enables epidermal growth factor receptor activity. Involved in several processes, including compound eye morphogenesis; open tracheal system development; and regionalization. Located in plasma membrane. Is active in apical plasma membrane. Colocalizes with cytoneme. Is expressed in several structures, including anlage in statu nascendi; anterior-posterior subdivision of organism; epithelium; gut section; and imaginal disc. Used to study alcohol use disorder; carcinoma; cardiomyopathy; and intestinal cancer. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); carcinoma (multiple); gastrointestinal system cancer (multiple); lung disease (multiple); and reproductive organ cancer (multiple). Orthologous to several human genes including ERBB4 (erb-b2 receptor tyrosine kinase 4). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to Egfr

NCBI Orthologs

How was this calculated?

genes for:

Protein alignment

Align

Download data

Download
Species Gene Architecture aa