IL16 interleukin 16 [Gallus gallus (chicken)] - Gene

Summary

Symbol: IL16provided by CGNC
Full Name: interleukin 16provided by CGNC
Primary source: CGNC:4808
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: interleukin-16
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	10	NC_052541.1 (12119632..12160467, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	10	NC_052582.1 (11997682..12038519, complement)

Chromosome 10 - NC_052541.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Changes in serum levels of IL-16 are associated with tumor development and tumor-associated neoangiogenesis (TAN). Thus, serum IL-16 levels may be an indicator of ovarian TAN at the early stage of ovarian cancer
Title: Association of interleukin 16 with the development of ovarian tumor and tumor-associated neoangiogenesis in laying hen model of spontaneous ovarian cancer.
pro-IL-16, expressed in COS-7 cells, showed chemoattractant activity for splenic lymphocytes.
Title: Identification and characterization of chicken interleukin-16 cDNA.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables CD4 receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables cytokine activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in induction of positive chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in leukocyte chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: pro-interleukin-16

Names: interleukin 16 (lymphocyte chemoattractant factor)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001277996.2 → NP_001264925.2 pro-interleukin-16

Status: VALIDATED

Source sequence(s)

JAENSK010000245

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052541.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

12119632..12160467 complement

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Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052582.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

11997682..12038519 complement

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GenBank, FASTA, Sequence Viewer (Graphics)