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Tmtc3 - Transmembrane O-mannosyltransferase targeting cadherins 3

Predicted to enable dolichyl-phosphate-mannose-protein mannosyltransferase activity. Predicted to be involved in protein O-linked mannosylation. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including central brain primordium; embryonic head sensory system; ganglia; larval nervous system; and ventral nerve cord primordium. Used to study epilepsy. Human ortholog(s) of this gene implicated in lissencephaly 8. Orthologous to human TMTC3 (transmembrane O-mannosyltransferase targeting cadherins 3). [provided by Alliance of Genome Resources, Oct 2024]

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Species Gene Architecture aa