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ND-B14.7 NADH dehydrogenase (ubiquinone) B14.7 subunit [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37385, updated on 14-Nov-2024

Summary

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Official Symbol
ND-B14.7provided by FlyBase
Official Full Name
NADH dehydrogenase (ubiquinone) B14.7 subunitprovided by FlyBase
Primary source
FLYBASE:FBgn0034576
Locus tag
Dmel_CG9350
See related
AllianceGenome:FB:FBgn0034576
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RH51452; CG9350; Dmel\CG9350; dNDUFA11; NDUFA11
Summary
Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Part of respiratory chain complex I. Is expressed in adult head and adult heart. Human ortholog(s) of this gene implicated in communication disorder and nuclear type mitochondrial complex I deficiency 14. Orthologous to human NDUFA11 (NADH:ubiquinone oxidoreductase subunit A11). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

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See ND-B14.7 in Genome Data Viewer
Location:
57B12-57B12; 2-92 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21025078..21026086)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16912583..16913591)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Souji Neighboring gene RIC3 acetylcholine receptor chaperone Neighboring gene long non-coding RNA:CR45148 Neighboring gene shotgun

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Generation of Mutants from the 57B Region of Drosophila melanogaster. Steinmetz EL, et al. Genes (Basel), 2023 Nov 6. PMID 38002990, Free PMC Article
  2. Evolution of the Tim17 protein family. Žárský V, et al. Biol Direct, 2016 Oct 19. PMID 27760563, Free PMC Article
  3. Dissecting the concordant and disparate roles of NDUFAF3 and NDUFAF4 in mitochondrial complex I biogenesis. Murari A, et al. iScience, 2021 Aug 20. PMID 34386730, Free PMC Article
  4. The membrane domain of respiratory complex I accumulates during muscle aging in Drosophila melanogaster. Hossain KFB, et al. Sci Rep, 2022 Dec 27. PMID 36575244, Free PMC Article
  5. An antibody toolbox to track complex I assembly defines AIF's mitochondrial function. Murari A, et al. J Cell Biol, 2020 Oct 5. PMID 32936885, Free PMC Article

See all (49) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mitochondrial electron transport, NADH to ubiquinone IC
Inferred by Curator
more info
 PubMed 
involved_in mitochondrial respiratory chain complex I assembly IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in mitochondrial inner membrane IC
Inferred by Curator
more info
 PubMed 
part_of respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of respiratory chain complex I IDA
Inferred from Direct Assay
more info
 PubMed 
part_of respiratory chain complex I ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
NADH dehydrogenase (ubiquinone) B14.7 subunit
Names
CG9350-PA
NADH ubiquinone oxidoreductase B14.7
ND-B14.7-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    21025078..21026086
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137694.4 → NP_611538.1  NADH dehydrogenase (ubiquinone) B14.7 subunit [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611538.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7JYH3
    Related
    FBpp0071459
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7JYH3 Q7JYH3

Gene LinkOut

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