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CG11007 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37249, updated on 18-Sep-2024

Summary

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Official Symbol
CG11007provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0034455
Locus tag
Dmel_CG11007
See related
AllianceGenome:FB:FBgn0034455
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG11007
Summary
Predicted to enable disulfide oxidoreductase activity. Predicted to be active in membrane-bounded organelle. Is expressed in several structures, including anterior endoderm; embryonic brain; embryonic/larval midgut; embryonic/larval visceral muscle cell; and extended germ band embryo. Orthologous to human TMX2 (thioredoxin related transmembrane protein 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See CG11007 in Genome Data Viewer
Location:
56D14-56D14; 2-89 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19503068..19504594)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (15390573..15392099)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Rab escort protein Neighboring gene hippo Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44472 Neighboring gene transfer RNA:Histidine-GTG 1-5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The impact of genome variation and diet on the metabolic phenotype and microbiome composition of Drosophila melanogaster. Jehrke L, et al. Sci Rep, 2018 Apr 18. PMID 29670218, Free PMC Article
  2. Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. Çiçek IÖ, et al. Genetics, 2016 Mar. PMID 26801178, Free PMC Article
  3. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article
  4. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article
  5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables disulfide oxidoreductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG11007-PA
CG11007-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    19503068..19504594
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299688.1 → NP_001286617.1  uncharacterized protein Dmel_CG11007, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286617.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7JW12
    UniProtKB/TrEMBL
    A0A0B4LFY2
    Conserved Domains (1) summary
    cd02962
    Location:100 → 251
    TMX2; TMX2 family; composed of proteins similar to human TMX2, a 372-amino acid TRX-related transmembrane protein, identified and characterized through the cloning of its cDNA from a human fetal library. It contains a TRX domain but the redox active CXXC motif ...

  2. NM_137585.4 → NP_611429.1  uncharacterized protein Dmel_CG11007, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611429.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7JW12
    UniProtKB/TrEMBL
    A0A0B4LFY2
    Related
    FBpp0085660
    Conserved Domains (1) summary
    cd02962
    Location:100 → 251
    TMX2; TMX2 family; composed of proteins similar to human TMX2, a 372-amino acid TRX-related transmembrane protein, identified and characterized through the cloning of its cDNA from a human fetal library. It contains a TRX domain but the redox active CXXC motif ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4LFY2 A0A0B4LFY2
Q7JW12.1 Q7JW12

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