DptA Diptericin A [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: DptAprovided by FlyBase
Official Full Name: Diptericin Aprovided by FlyBase
Primary source: FLYBASE:FBgn0004240
Locus tag: Dmel_CG12763
See related: AllianceGenome:FB:FBgn0004240
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 143443_at; CG12763; Dep; DIM 27; dip; Dip; DipA; dipt; Dipt; DIPT; Dipt A; diptA; DiptA; diptericin; Diptericin; Dit; Dmel\CG12763; dpt; Dpt; DPT; dpt A; dptA; DtpA
Summary: Involved in antibacterial humoral response; defense response to Gram-negative bacterium; and response to hyperoxia. Is expressed in adult anterior midgut. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (18865765..18866260)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (14753270..14753765)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

activation controlled by Forkhead
Title: Forkhead, a new cross regulator of metabolism and innate immunity downstream of TOR in Drosophila.
This is a major protein involved in the Drosophila immune deficiency signaling cascade.
Title: A ubiquitin-proteasome pathway represses the Drosophila immune deficiency signaling cascade.
Diptericin expression is negatively affected by high bacterial infection dose and rapid bacterial growth.
Title: Diptericin expression in bacteria infected Drosophila mbn-2 cells - effect of infection dose and phagocytosis.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Process	Evidence Code	Pubs
involved_in antibacterial humoral response	IEP Inferred from Expression Pattern more info	PubMed
involved_in defense response to Gram-negative bacterium	HMP more info	PubMed
involved_in defense response to Gram-negative bacterium	IDA Inferred from Direct Assay more info	PubMed
involved_in defense response to Gram-negative bacterium	IEP Inferred from Expression Pattern more info	PubMed
involved_in defense response to bacterium	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in positive regulation of innate immune response	HMP more info	PubMed
involved_in response to bacterium	HEP more info	PubMed
involved_in response to bacterium	IDA Inferred from Direct Assay more info	PubMed
involved_in response to hyperoxia	IMP Inferred from Mutant Phenotype more info	PubMed