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B18R ankyrin-like protein [ Vaccinia virus ]

Gene ID: 3707576, updated on 18-Aug-2023

Summary

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Gene symbol
B18R
Gene description
ankyrin-like protein
Locus tag
VACWR199
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Vaccinia virus (strain: WR (Western Reserve))
Lineage
Viruses; dsDNA viruses, no RNA stage; Poxviridae; Chordopoxvirinae; Orthopoxvirus
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Genomic context

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Sequence:
NC_006998.1 (177306..179030)

NC_006998.1Genomic Context describing neighboring genes Neighboring gene IL-beta-binding protein Neighboring gene hypothetical protein Neighboring gene temporal expression: early Neighboring gene hypothetical protein Neighboring gene ankyrin-like protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_006998.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Vaccinia virus-mediated inhibition of type I interferon responses is a multifactorial process involving the soluble type I interferon receptor B18 and intracellular components. Waibler Z, et al. J Virol, 2009 Feb. PMID 19073732, Free PMC Article
  2. The vaccinia virus 42-kDa envelope protein is required for the envelopment and egress of extracellular virus and for virus virulence. Engelstad M, et al. Virology, 1993 Jun. PMID 8503178
  3. Dissociation of progeny vaccinia virus from the cell membrane is regulated by a viral envelope glycoprotein: effect of a point mutation in the lectin homology domain of the A34R gene. Blasco R, et al. J Virol, 1993 Jun. PMID 8497053, Free PMC Article
  4. Characterization of vaccinia surface antigen expressed by recombinant baculovirus. Morikawa S, et al. Virology, 1993 Apr. PMID 8460484
  5. Deletion of the vaccinia virus B5R gene encoding a 42-kilodalton membrane glycoprotein inhibits extracellular virus envelope formation and dissemination. Wolffe EJ, et al. J Virol, 1993 Aug. PMID 8331727, Free PMC Article

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Collectively, the data presented show that VACV-mediated IFN inhibition is a multistep process involving secreted factors such as B18 plus intracellular components that cooperate to efficiently shut off systemic IFN-alpha and IFN-beta responses.
    Title: Vaccinia virus-mediated inhibition of type I interferon responses is a multifactorial process involving the soluble type I interferon receptor B18 and intracellular components.
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General gene information

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Homology

General protein information

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Preferred Names
ankyrin-like protein
YP_233081.1
  • similar to VACCP-B18R

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_006998.1 Reference assembly

    Range
    177306..179030
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_233081.1 ankyrin-like protein [Vaccinia virus]

    See identical proteins and their annotated locations for YP_233081.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O57263, Q01222, Q76ZK6
    UniProtKB/TrEMBL
    A0A2I2ME56, A0A2I6TE47
    Conserved Domains (3) summary
    sd00045
    Location:167 → 215
    ANK; ANK repeat [structural motif]
    cl26073
    Location:139 → 567
    Ank_2; Ankyrin repeats (3 copies)
    cl26074
    Location:40 → 163
    PHA02859; ankyrin repeat protein; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
AAO89478.1

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