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dpy-10 Cuticle collagen dpy-10 [ Caenorhabditis elegans ]

Gene ID: 36805042, updated on 18-Sep-2024

Summary

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Official Symbol
dpy-10
Official Full Name
Cuticle collagen dpy-10
Primary source
WormBase:WBGene00001072
Locus tag
CELE_T14B4.7
See related
AllianceGenome:WB:WBGene00001072
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be a structural constituent of collagen and cuticulin-based cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle; locomotion; and post-embryonic body morphogenesis. Predicted to be part of collagen trimer. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See dpy-10 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003280.10 (6710149..6712227, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene 43 kDa receptor-associated protein of the synapse homolog Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Tantalus domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Reliable CRISPR/Cas9 Genome Engineering in Caenorhabditis elegans Using a Single Efficient sgRNA and an Easily Recognizable Phenotype. El Mouridi S, et al. G3 (Bethesda), 2017 May 5. PMID 28280211, Free PMC Article
  2. Extending the CRISPR toolbox for C. elegans: Cpf1 as an alternative gene editing system for AT-rich sequences. Ebbing A, et al. MicroPubl Biol, 2017 Dec 1. PMID 32550354, Free PMC Article
  3. Efficient marker-free recovery of custom genetic modifications with CRISPR/Cas9 in Caenorhabditis elegans. Arribere JA, et al. Genetics, 2014 Nov. PMID 25161212, Free PMC Article
  4. Activation of a G protein-coupled receptor by its endogenous ligand triggers the innate immune response of Caenorhabditis elegans. Zugasti O, et al. Nat Immunol, 2014 Sep. PMID 25086774, Free PMC Article
  5. Metabotyping of Caenorhabditis elegans reveals latent phenotypes. Blaise BJ, et al. Proc Natl Acad Sci U S A, 2007 Dec 11. PMID 18077412, Free PMC Article

See all (71) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables structural constituent of collagen and cuticulin-based cuticle ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables structural constituent of cuticle IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of cuticle NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in collagen and cuticulin-based cuticle development NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in cuticle development involved in collagen and cuticulin-based cuticle molting cycle IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in locomotion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in post-embryonic body morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of collagen trimer IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular region NAS
Non-traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
Cuticle collagen dpy-10
NP_001335511.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    6710149..6712227 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001348636.5 → NP_001335511.1  Cuticle collagen dpy-10 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P35800, Q22476
    Conserved Domains (1) summary
    pfam01484
    Location:32 → 72
    Col_cuticle_N; Nematode cuticle collagen N-terminal domain
Nucleotide Protein
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