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Gadl1 glutamate decarboxylase-like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 367181, updated on 17-Aug-2024

Summary

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Symbol
Gadl1provided by RGD
Full Name
glutamate decarboxylase-like 1provided by RGD
Primary source
RGD:1565145
See related
EnsemblRapid:ENSRNOG00000067908 AllianceGenome:RGD:1565145
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1565145
Summary
Orthologous to human GADL1 (glutamate decarboxylase like 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 185.3) See more
Orthologs
human mouse all
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Genomic context

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Location:
8q32
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (124483736..124663815)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (115605609..115785676)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (123989822..124301366)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134480108 Neighboring gene uncharacterized LOC120094283 Neighboring gene transforming growth factor, beta receptor 2 Neighboring gene uncharacterized LOC120094284

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables carboxy-lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carboxylic acid metabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
acidic amino acid decarboxylase GADL1; glutamate decarboxylase-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001430390.1 → NP_001417319.1  glutamate decarboxylase-like 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    A0A8I6AWC8

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    124483736..124663815
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008766660.4 → XP_008764882.3  acidic amino acid decarboxylase GADL1 isoform X1

    Related
    ENSRNOP00000102931.1, ENSRNOT00000172052.1
    Conserved Domains (1) summary
    cd06450
    Location:196 → 596
    DOPA_deC_like; DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and ...

  2. XM_039082694.2 → XP_038938622.1  acidic amino acid decarboxylase GADL1 isoform X2

    UniProtKB/TrEMBL
    A0A8I6AWC8
    Conserved Domains (1) summary
    cd06450
    Location:98 → 498
    DOPA_deC_like; DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and ...

  3. XM_039082695.2 → XP_038938623.1  acidic amino acid decarboxylase GADL1 isoform X2

    UniProtKB/TrEMBL
    A0A8I6AWC8
    Related
    ENSRNOP00000097428.2, ENSRNOT00000117193.2
    Conserved Domains (1) summary
    cd06450
    Location:98 → 498
    DOPA_deC_like; DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and ...
Nucleotide Protein Strain
Heading Accession and Version

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