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Esf1 ESF1 nucleolar pre-rRNA processing protein homolog [ Rattus norvegicus (Norway rat) ]

Gene ID: 366203, updated on 2-Nov-2024

Summary

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Official Symbol
Esf1provided by RGD
Official Full Name
ESF1 nucleolar pre-rRNA processing protein homologprovided by RGD
Primary source
RGD:1306067
See related
EnsemblRapid:ENSRNOG00000004777 AllianceGenome:RGD:1306067
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1306067
Summary
Predicted to enable RNA binding activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleolus and nucleoplasm. Orthologous to human ESF1 (ESF1 nucleolar pre-rRNA processing protein homolog). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 56.4), Muscle (RPKM 56.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Esf1 in Genome Data Viewer
Location:
3q36-q41
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (147908405..147961567, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (127454744..127507941, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (133178591..133232358, complement)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120101716 Neighboring gene taspase 1 Neighboring gene Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 87 Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 5 Neighboring gene SEL1L2 adaptor subunit of SYVN1 ubiquitin ligase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. ABT1-associated protein (ABTAP), a novel nuclear protein conserved from yeast to mammals, represses transcriptional activation by ABT1. Oda T, et al. J Cell Biochem, 2004 Nov 1. PMID 15660422
  2. Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy. Pieragostino D, et al. Mol Biosyst, 2013 Jun. PMID 23580065
  3. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ESF1 homolog
Names
ABT1-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100771.2 → NP_001094241.1  ESF1 homolog

    See identical proteins and their annotated locations for NP_001094241.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/Swiss-Prot
    Q76MT4
    UniProtKB/TrEMBL
    A6HQL9
    Related
    ENSRNOP00000037915.4, ENSRNOT00000034487.7
    Conserved Domains (2) summary
    COG5638
    Location:293 → 827
    COG5638; Uncharacterized conserved protein [Function unknown]
    pfam08159
    Location:750 → 778
    NUC153; NUC153 domain

  2. NM_001434428.1 → NP_001421357.1  ESF1 homolog

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003

  3. NM_001434429.1 → NP_001421358.1  ESF1 homolog

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    147908405..147961567 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006235106.4 → XP_006235168.1  ESF1 homolog isoform X1

    UniProtKB/Swiss-Prot
    Q76MT4
    UniProtKB/TrEMBL
    A6HQL9
    Conserved Domains (2) summary
    COG5638
    Location:293 → 827
    COG5638; Uncharacterized conserved protein [Function unknown]
    pfam08159
    Location:750 → 778
    NUC153; NUC153 domain

  2. XM_063284287.1 → XP_063140357.1  ESF1 homolog isoform X1

    UniProtKB/Swiss-Prot
    Q76MT4
    UniProtKB/TrEMBL
    A6HQL9

  3. XM_006235105.5 → XP_006235167.1  ESF1 homolog isoform X1

    UniProtKB/Swiss-Prot
    Q76MT4
    UniProtKB/TrEMBL
    A6HQL9
    Conserved Domains (2) summary
    COG5638
    Location:293 → 827
    COG5638; Uncharacterized conserved protein [Function unknown]
    pfam08159
    Location:750 → 778
    NUC153; NUC153 domain

  4. XM_017591950.3 → XP_017447439.1  ESF1 homolog isoform X1

    UniProtKB/Swiss-Prot
    Q76MT4
    UniProtKB/TrEMBL
    A6HQL9
    Conserved Domains (2) summary
    COG5638
    Location:293 → 827
    COG5638; Uncharacterized conserved protein [Function unknown]
    pfam08159
    Location:750 → 778
    NUC153; NUC153 domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q76MT4.1 GenPept UniProtKB/Swiss-Prot:Q76MT4

Gene LinkOut

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