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subA subtilase cytotoxin, subunit A [ Escherichia coli ]

Gene ID: 3654564, discontinued on 15-Jul-2020
  • This record was discontinued.

Summary

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Gene symbol
subA
Gene description
subtilase cytotoxin, subunit A
Locus tag
LH0183
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli (strain: EH41, serotype: O113:H21)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
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Genomic context

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Location:
plasmid: pO113
Sequence:
NC_007365.1 (151027..152070, complement)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_007365.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ability of SubAB to selectively induce the unfolded protein response, preventing LPS-associated inflammatory pathology
    Title: A subcytotoxic dose of subtilase cytotoxin prevents lipopolysaccharide-induced inflammatory responses, depending on its capacity to induce the unfolded protein response.
  2. findings raise the possibility that SubAB (subtilase cytotoxin) directly contributes to pathology in humans infected with strains of STEC that produce both Shiga toxin and SubAB
    Title: Pathologic changes in mice induced by subtilase cytotoxin, a potent new Escherichia coli AB5 toxin that targets the endoplasmic reticulum.
Submit: New GeneRIF Correction

General protein information

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Preferred Names
subtilase cytotoxin, subunit A
YP_308822.1
  • predicted subcellular location is secreted

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_007365.1 Reference assembly

    Range
    151027..152070 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_308822.1 subtilase cytotoxin, subunit A [Escherichia coli]

    Status: PROVISIONAL

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Research Materials