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SKO1 Sko1p [ Candida albicans SC5314 ]

Gene ID: 3644688, updated on 30-Nov-2023

Summary

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Gene symbol
SKO1
Gene description
Sko1p
Locus tag
CAALFM_C103770WA
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Candida albicans SC5314 (strain: SC5314, nat-host: Homo sapiens, culture-collection: ATCC:MYA-2876)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida
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Genomic context

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See SKO1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
2
Sequence:
Chromosome: 1; NC_032089.1 (788296..790142)

Chromosome 1 - NC_032089.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene cystathionine gamma-synthase Neighboring gene hydroxymethylglutaryl-CoA reductase (NADPH) Neighboring gene peptidylprolyl isomerase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_032089.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptional regulation of the caspofungin-induced cell wall damage response in Candida albicans. Heredia MY, et al. Curr Genet, 2020 Dec. PMID 32876716, Free PMC Article
  2. Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure. Muzzey D, et al. Genome Biol, 2013. PMID 24025428, Free PMC Article
  3. Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes. van het Hoog M, et al. Genome Biol, 2007. PMID 17419877, Free PMC Article
  4. The diploid genome sequence of Candida albicans. Jones T, et al. Proc Natl Acad Sci U S A, 2004 May 11. PMID 15123810, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Transcriptional regulation of the caspofungin-induced cell wall damage response in Candida albicans.
    Title: Transcriptional regulation of the caspofungin-induced cell wall damage response in Candida albicans.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
Sko1p
XP_019330633.1
  • bZIP transcription factor; involved in cell wall damage response; represses the yeast-to-hypha transition; mutants are caspofungin sensitive; induced by osmotic stress via Hog1; induced by Mnl1 under weak acid stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_032089.1 Reference assembly

    Range
    788296..790142
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019475088.1 → XP_019330633.1  Sko1p [Candida albicans SC5314]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    A0A1D8PD41, Q59VR1
    UniProtKB/TrEMBL
    A0A8H6F139
    Conserved Domains (2) summary
    cd14687
    Location:485 → 541
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    pfam11786
    Location:175 → 199
    Aft1_HRA; Aft1 HRA domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials