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SEP7 septin [ Candida albicans SC5314 ]

Gene ID: 3644596, updated on 30-Nov-2023

Summary

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Gene symbol
SEP7
Gene description
septin
Locus tag
CAALFM_C102230WA
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Candida albicans SC5314 (strain: SC5314, nat-host: Homo sapiens, culture-collection: ATCC:MYA-2876)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida
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Genomic context

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See SEP7 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
1
Sequence:
Chromosome: 1; NC_032089.1 (465637..467649)

Chromosome 1 - NC_032089.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene NADHX epimerase Neighboring gene karyopherin beta Neighboring gene Cwh8p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_032089.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sep7 is essential to modify septin ring dynamics and inhibit cell separation during Candida albicans hyphal growth. González-Novo A, et al. Mol Biol Cell, 2008 Apr. PMID 18234840, Free PMC Article
  2. Tpd3-Pph21 phosphatase plays a direct role in Sep7 dephosphorylation in Candida albicans. Liu Q, et al. Mol Microbiol, 2016 Jul. PMID 26991697
  3. Tandem affinity purification of the Candida albicans septin protein complex. Kaneko A, et al. Yeast, 2004 Sep. PMID 15449307
  4. A single nucleotide polymorphism uncovers a novel function for the transcription factor Ace2 during Candida albicans hyphal development. Calderón-Noreña DM, et al. PLoS Genet, 2015 Apr. PMID 25875512, Free PMC Article
  5. Cyclin-dependent kinases control septin phosphorylation in Candida albicans hyphal development. Sinha I, et al. Dev Cell, 2007 Sep. PMID 17765684

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables molecular adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actomyosin contractile ring assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular bud neck septin ring organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytoskeleton-dependent cytokinesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in division septum assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to bud neck IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell division site IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in microtubule cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of septin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in septin ring IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
septin
XP_713774.1
  • Septin, required for wild-type invasive growth in vitro but not required for virulence in a mouse model of systemic infection; localizes to hyphal septum or bud neck; Asn-rich; aberrant gel mobility; phosphorylated in vitro by Gin4p

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_032089.1 Reference assembly

    Range
    465637..467649
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_708681.2 → XP_713774.1  septin [Candida albicans SC5314]

    See identical proteins and their annotated locations for XP_713774.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    A0A1D8PCP5, Q59VX8
    UniProtKB/TrEMBL
    C4YF49
    Conserved Domains (1) summary
    cd01850
    Location:33 → 358
    CDC_Septin; CDC/Septin GTPase family
Nucleotide Protein
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