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YPD1 Ypd1p [ Candida albicans SC5314 ]

Gene ID: 3644458, updated on 30-Nov-2023

Summary

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Gene symbol
YPD1
Gene description
Ypd1p
Locus tag
CAALFM_C107240WA
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Candida albicans SC5314 (strain: SC5314, nat-host: Homo sapiens, culture-collection: ATCC:MYA-2876)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida
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Genomic context

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See YPD1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
1
Sequence:
Chromosome: 1; NC_032089.1 (1553508..1554062)

Chromosome 1 - NC_032089.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene 4-nitrophenylphosphatase Neighboring gene dolichyl-P-Man:Man(6)GlcNAc(2)-PP-dolichol alpha-1,2-mannosyltransferase Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_032089.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Two-component histidine phosphotransfer protein Ypd1 is not essential for viability in Candida albicans. Mavrianos J, et al. Eukaryot Cell, 2014 Apr. PMID 24489039, Free PMC Article
  2. Blocking two-component signalling enhances Candida albicans virulence and reveals adaptive mechanisms that counteract sustained SAPK activation. Day AM, et al. PLoS Pathog, 2017 Jan. PMID 28135328, Free PMC Article
  3. Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure. Muzzey D, et al. Genome Biol, 2013. PMID 24025428, Free PMC Article
  4. Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes. van het Hoog M, et al. Genome Biol, 2007. PMID 17419877, Free PMC Article
  5. The diploid genome sequence of Candida albicans. Jones T, et al. Proc Natl Acad Sci U S A, 2004 May 11. PMID 15123810, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Drug-mediated repression of YPD1 expression promotes hyphal growth both within murine kidneys, and following phagocytosis, thus increasing the efficacy by which Candida albicans kills macrophages.
    Title: Blocking two-component signalling enhances Candida albicans virulence and reveals adaptive mechanisms that counteract sustained SAPK activation.
  2. Ypd1 is not essential for viability in Candida albicans.
    Title: Two-component histidine phosphotransfer protein Ypd1 is not essential for viability in Candida albicans.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histidine phosphotransfer kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein histidine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphorelay signal transduction system IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
Ypd1p
XP_713887.1
  • Phosphohistidine intermediate protein in a phosphorelay signal transduction pathway; residue His69 is the phosphoacceptor histidine; predicted to be soluble and cytosolic; functional homolog of S. cerevisiae Ypd1p

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_032089.1 Reference assembly

    Range
    1553508..1554062
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_708794.1 → XP_713887.1  Ypd1p [Candida albicans SC5314]

    See identical proteins and their annotated locations for XP_713887.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    A0A1D8PE42, G1UAK5, Q59WC6, Q9HGV5
    UniProtKB/TrEMBL
    A0A8H6F0D2, C4YDU4
    Conserved Domains (1) summary
    cd00088
    Location:35 → 108
    HPT; Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is ...
Nucleotide Protein
Heading Accession and Version

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