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EFT2 elongation factor 2 [ Candida albicans SC5314 ]

Gene ID: 3642998, updated on 30-Nov-2023

Summary

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Gene symbol
EFT2
Gene description
elongation factor 2
Locus tag
CAALFM_C203100WA
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Candida albicans SC5314 (strain: SC5314, nat-host: Homo sapiens, culture-collection: ATCC:MYA-2876)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida
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Genomic context

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See EFT2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
2
Sequence:
Chromosome: 2; NC_032090.1 (623498..626224)

Chromosome 2 - NC_032090.1Genomic Context describing neighboring genes Neighboring gene isocitrate dehydrogenase (NAD(+)) Neighboring gene phosphoribosylglycinamide formyltransferase Neighboring gene uncharacterized protein Neighboring gene Amo1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_032090.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A functional portrait of Med7 and the mediator complex in Candida albicans. Tebbji F, et al. PLoS Genet, 2014 Nov. PMID 25375174, Free PMC Article
  2. Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fungal pathogen. O'Meara TR, et al. PLoS Biol, 2019 Jul. PMID 31283755, Free PMC Article
  3. Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure. Muzzey D, et al. Genome Biol, 2013. PMID 24025428, Free PMC Article
  4. Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes. van het Hoog M, et al. Genome Biol, 2007. PMID 17419877, Free PMC Article
  5. The diploid genome sequence of Candida albicans. Jones T, et al. Proc Natl Acad Sci U S A, 2004 May 11. PMID 15123810, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ribosome binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables translation elongation factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in translational elongation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
elongation factor 2
XP_019330758.1
  • Elongation Factor 2 (eEF2); GTPase; essential; highly expressed; target of sordarin antifungals; antigenic in human/mouse; lacks site for regulatory phosphorylation by eEF2 kinase; GCN-regulated; higher protein amount in stationary phase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_032090.1 Reference assembly

    Range
    623498..626224
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019475213.1 → XP_019330758.1  elongation factor 2 [Candida albicans SC5314]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    A0A1D8PGT9, C4YJQ8, O13430, Q5A0M4, Q9P4S4
    UniProtKB/TrEMBL
    A0A8H6BU35
    Conserved Domains (1) summary
    PTZ00416
    Location:1 → 842
    PTZ00416; elongation factor 2; Provisional
Nucleotide Protein
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