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AUR1 inositol phosphorylceramide synthase [ Candida albicans SC5314 ]

Gene ID: 3642617, updated on 30-Nov-2023

Summary

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Gene symbol
AUR1
Gene description
inositol phosphorylceramide synthase
Locus tag
CAALFM_C501240WA
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Candida albicans SC5314 (strain: SC5314, nat-host: Homo sapiens, culture-collection: ATCC:MYA-2876)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida
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Genomic context

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See AUR1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
1
Sequence:
Chromosome: 5; NC_032093.1 (276990..278405)

Chromosome 5 - NC_032093.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene glucose-6-phosphate 1-epimerase Neighboring gene Gpr1p Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_032093.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure. Muzzey D, et al. Genome Biol, 2013. PMID 24025428, Free PMC Article
  2. Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes. van het Hoog M, et al. Genome Biol, 2007. PMID 17419877, Free PMC Article
  3. The diploid genome sequence of Candida albicans. Jones T, et al. Proc Natl Acad Sci U S A, 2004 May 11. PMID 15123810, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inositol phosphoceramide synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in inositol phosphoceramide metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphingolipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of inositol phosphoceramide synthase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
inositol phosphorylceramide synthase
XP_715708.1
  • Inositolphosphorylceramide (IPC) synthase; catalyzes the key step in sphingolipid biosynthesis; antifungal drug target; flow model biofilm induced; Spider biofilm induced

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_032093.1 Reference assembly

    Range
    276990..278405
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_710615.2 → XP_715708.1  inositol phosphorylceramide synthase [Candida albicans SC5314]

    See identical proteins and their annotated locations for XP_715708.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    A0A1D8PN38, O13332, Q5A1Q1
    UniProtKB/TrEMBL
    A0A8H6BTW1, C4YR14
    Conserved Domains (1) summary
    cd03386
    Location:135 → 328
    PAP2_Aur1_like; PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin.
Nucleotide Protein
Heading Accession and Version

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