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CHS2 chitin synthase [ Candida albicans SC5314 ]

Gene ID: 3641893, updated on 26-Jun-2024

Summary

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Gene symbol
CHS2
Gene description
chitin synthase
Locus tag
CAALFM_CR09020CA
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Candida albicans SC5314 (strain: SC5314, nat-host: Homo sapiens, culture-collection: ATCC:MYA-2876)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida
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Genomic context

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See CHS2 in Genome Data Viewer
Location:
chromosome: R
Exon count:
1
Sequence:
Chromosome: R; NC_032096.1 (1926708..1929737, complement)

Chromosome R - NC_032096.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene putative cystathionine beta-lyase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_032096.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Stimulation of chitin synthesis rescues Candida albicans from echinocandins. Walker LA, et al. PLoS Pathog, 2008 Apr 4. PMID 18389063, Free PMC Article
  2. Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure. Muzzey D, et al. Genome Biol, 2013. PMID 24025428, Free PMC Article
  3. Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes. van het Hoog M, et al. Genome Biol, 2007. PMID 17419877, Free PMC Article
  4. The diploid genome sequence of Candida albicans. Jones T, et al. Proc Natl Acad Sci U S A, 2004 May 11. PMID 15123810, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chitin synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell periphery IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell septum IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
chitin synthase
XP_716433.1
  • Chitin synthase; nonessential; required for wild-type chitin deposition in hyphae; transcript regulated during dimorphic transition; Chs1 and Chs2, but not Chs3, are inhibited by the protoberberine HWY-289; flow model biofilm repressed

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_032096.1 Reference assembly

    Range
    1926708..1929737 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_711340.1 → XP_716433.1  chitin synthase [Candida albicans SC5314]

    See identical proteins and their annotated locations for XP_716433.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P30572
    UniProtKB/TrEMBL
    A0A1D8PTV3
    Conserved Domains (4) summary
    COG1215
    Location:431 → 775
    BcsA; Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility]
    pfam01644
    Location:319 → 482
    Chitin_synth_1; Chitin synthase
    pfam08407
    Location:236 → 317
    Chitin_synth_1N; Chitin synthase N-terminal
    cl11394
    Location:460 → 702
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Other Literature Sources
Molecular Biology Databases
Research Materials