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Ak6 Adenylate kinase 6 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36379, updated on 28-Oct-2024

Summary

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Official Symbol
Ak6provided by FlyBase
Official Full Name
Adenylate kinase 6provided by FlyBase
Primary source
FLYBASE:FBgn0033754
Locus tag
Dmel_CG8816
See related
AllianceGenome:FB:FBgn0033754
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG8816; DAK6; Dmel\CG8816
Summary
Enables adenylate kinase activity. Located in nucleus. Orthologous to human AK6 (adenylate kinase 6). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
all
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Genomic context

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See Ak6 in Genome Data Viewer
Location:
49B5-49B5; 2-67 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12569014..12569847, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8456519..8457352, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene frazzled Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cytochrome P450 301a1 Neighboring gene stand still Neighboring gene Chloride channel-b Neighboring gene Sin3A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of a novel nuclear-localized adenylate kinase from Drosophila melanogaster. Meng G, et al. Biochemistry (Mosc), 2008 Jan. PMID 18294127
  2. Transcriptional response to dietary restriction in Drosophila melanogaster. Ding F, et al. J Insect Physiol, 2014 Oct. PMID 24819200, Free PMC Article
  3. Negative genetic correlation between longevity and its hormetic extension by dietary restriction in Drosophila melanogaster. Gomez FH, et al. Biogerontology, 2020 Apr. PMID 31786681
  4. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
  5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables adenylate kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables adenylate kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables adenylate kinase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
adenylate kinase 6
Names
Ak6-PA
CG8816-PA
NP_610797.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    12569014..12569847 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136953.4 → NP_610797.1  adenylate kinase 6 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610797.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7JYV7
    Related
    FBpp0087004
    Conserved Domains (1) summary
    COG1936
    Location:10 → 173
    Fap7; Broad-specificity NMP kinase [Nucleotide transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7JYV7.1 Q7JYV7

Gene LinkOut

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