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CG8850 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36331, updated on 2-Nov-2024

Summary

Official Symbol
CG8850provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033708
Locus tag
Dmel_CG8850
See related
AllianceGenome:FB:FBgn0033708
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG8850; DmNAT4
Summary
Predicted to enable L-amino acid transmembrane transporter activity; amino acid:sodium symporter activity; and neurotransmitter transmembrane transporter activity. Predicted to be involved in glycine import across plasma membrane; neurotransmitter transport; and sodium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult abdomen; adult head; adult thorax; embryonic Malpighian tubule; and embryonic main segment of Malpighian tubule. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See CG8850 in Genome Data Viewer
Location:
48F6-48F6; 2-66 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12298747..12302240, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8186252..8189745, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43900 Neighboring gene Calmodulin Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45271 Neighboring gene salto Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables amino acid:monoatomic cation symporter activity ISM
Inferred from Sequence Model
more info
PubMed 
enables amino acid:sodium symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables neurotransmitter transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
involved_in amino acid transmembrane transport ISM
Inferred from Sequence Model
more info
PubMed 
involved_in glycine import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in neurotransmitter transport ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in sodium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane ISM
Inferred from Sequence Model
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
uncharacterized protein
Names
CG8850-PA
CG8850-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    12298747..12302240 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_165871.3NP_725122.2  uncharacterized protein Dmel_CG8850, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_725122.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z8V9, B6CLF6
    Related
    FBpp0087080
    Conserved Domains (1) summary
    cd10324
    Location:58532
    SLC6sbd; Solute carrier 6 family, neurotransmitter transporters; solute-binding domain
  2. NM_136911.3NP_610755.2  uncharacterized protein Dmel_CG8850, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610755.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z8W0, B6CLF6
    Related
    FBpp0087081
    Conserved Domains (1) summary
    cd10324
    Location:45519
    SLC6sbd; Solute carrier 6 family, neurotransmitter transporters; solute-binding domain