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Ppfia2 PTPRF interacting protein alpha 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362876, updated on 10-Oct-2024

Summary

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Official Symbol
Ppfia2provided by RGD
Official Full Name
PTPRF interacting protein alpha 2provided by RGD
Primary source
RGD:1305021
See related
EnsemblRapid:ENSRNOG00000004353 AllianceGenome:RGD:1305021
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
A structural constituent of presynapse. Involved in regulation of synaptic vesicle exocytosis. Is active in glutamatergic synapse. Orthologous to human PPFIA2 (PTPRF interacting protein alpha 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 159.9), Adrenal (RPKM 28.3) and 1 other tissue See more
Orthologs
human mouse all
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Genomic context

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See Ppfia2 in Genome Data Viewer
Location:
7q21
Exon count:
36
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (43652258..44126555)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (41765716..42240104)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (48548932..49045852)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479681 Neighboring gene methyltransferase like 25 Neighboring gene coiled-coil domain containing 59 Neighboring gene uncharacterized LOC134479682 Neighboring gene sulfotransferase 1C2 pseudogene Neighboring gene acyl-CoA synthetase short-chain family member 3 Neighboring gene small nucleolar RNA SNORA17

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission. Spangler SA, et al. J Cell Biol, 2013 Jun 10. PMID 23751498, Free PMC Article
  2. Liprin-α3 controls vesicle docking and exocytosis at the active zone of hippocampal synapses. Wong MY, et al. Proc Natl Acad Sci U S A, 2018 Feb 27. PMID 29439199, Free PMC Article
  3. Analyses of the spatiotemporal expression and subcellular localization of liprin-α proteins. Zürner M, et al. J Comp Neurol, 2011 Oct 15. PMID 21618221
  4. Regulation of KIF1A-Driven Dense Core Vesicle Transport: Ca(2+)/CaM Controls DCV Binding and Liprin-α/TANC2 Recruits DCVs to Postsynaptic Sites. Stucchi R, et al. Cell Rep, 2018 Jul 17. PMID 30021165, Free PMC Article
  5. Interaction between GRIP and liprin-alpha/SYD2 is required for AMPA receptor targeting. Wyszynski M, et al. Neuron, 2002 Mar 28. PMID 11931740

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
  
enables structural constituent of postsynaptic density EXP
Inferred from Experiment
more info
 PubMed 
enables structural constituent of postsynaptic density IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of postsynaptic density IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables structural constituent of presynapse IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of presynapse IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in dense core granule cytoskeletal transport ISO
Inferred from Sequence Orthology
more info
  
involved_in maintenance of postsynaptic density structure IEA
Inferred from Electronic Annotation
more info
  
involved_in presynapse organization IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of dendritic spine development ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of dendritic spine morphogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of synaptic vesicle exocytosis IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of synaptic vesicle exocytosis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in synapse organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
  
located_in dendritic spine ISO
Inferred from Sequence Orthology
more info
  
is_active_in glutamatergic synapse EXP
Inferred from Experiment
more info
 PubMed 
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
 PubMed 
is_active_in glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
  
is_active_in postsynaptic density IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in postsynaptic density IMP
Inferred from Mutant Phenotype
more info
 PubMed 
is_active_in postsynaptic specialization IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in presynaptic active zone IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in presynaptic cytosol ISO
Inferred from Sequence Orthology
more info
  
is_active_in presynaptic membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
  
located_in synapse ISO
Inferred from Sequence Orthology
more info
  
is_active_in synaptic vesicle IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
liprin-alpha-2
Names
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108745.1 → NP_001102215.1  liprin-alpha-2

    See identical proteins and their annotated locations for NP_001102215.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473960
    UniProtKB/TrEMBL
    A6IGB9, F1M8A4
    Conserved Domains (6) summary
    cd09562
    Location:895 → 965
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:1013 → 1078
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1098 → 1169
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    smart00454
    Location:895 → 961
    SAM; Sterile alpha motif
    pfam09728
    Location:265 → 533
    Taxilin; Myosin-like coiled-coil protein
    cl02488
    Location:261 → 452
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    43652258..44126555
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063263774.1 → XP_063119844.1  liprin-alpha-2 isoform X1

  2. XM_063263778.1 → XP_063119848.1  liprin-alpha-2 isoform X3

  3. XM_063263775.1 → XP_063119845.1  liprin-alpha-2 isoform X1

  4. XM_063263786.1 → XP_063119856.1  liprin-alpha-2 isoform X12

    UniProtKB/TrEMBL
    A0A8I6AK94
    Related
    ENSRNOP00000094445.2, ENSRNOT00000108079.2

  5. XM_063263779.1 → XP_063119849.1  liprin-alpha-2 isoform X3

  6. XM_063263790.1 → XP_063119860.1  liprin-alpha-2 isoform X18

  7. XM_063263780.1 → XP_063119850.1  liprin-alpha-2 isoform X5

  8. XM_039079448.2 → XP_038935376.1  liprin-alpha-2 isoform X4

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:928 → 998
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:1046 → 1111
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1131 → 1202
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:201 → 566
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:454 → 721
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  9. XM_063263782.1 → XP_063119852.1  liprin-alpha-2 isoform X7

  10. XM_063263781.1 → XP_063119851.1  liprin-alpha-2 isoform X6

  11. XM_039079446.2 → XP_038935374.1  liprin-alpha-2 isoform X2

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:927 → 997
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:1051 → 1116
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1136 → 1207
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:201 → 566
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:454 → 721
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  12. XM_063263784.1 → XP_063119854.1  liprin-alpha-2 isoform X9

  13. XM_063263777.1 → XP_063119847.1  liprin-alpha-2 isoform X3

  14. XM_063263785.1 → XP_063119855.1  liprin-alpha-2 isoform X10

  15. XM_063263787.1 → XP_063119857.1  liprin-alpha-2 isoform X13

  16. XM_063263788.1 → XP_063119858.1  liprin-alpha-2 isoform X15

  17. XM_017594921.3 → XP_017450410.1  liprin-alpha-2 isoform X11

    UniProtKB/TrEMBL
    F1M8A4

  18. XM_039079457.2 → XP_038935385.1  liprin-alpha-2 isoform X14

    UniProtKB/TrEMBL
    A0A8I6AM56, F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:894 → 964
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:1018 → 1083
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1103 → 1174
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:87 → 471
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:265 → 685
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  19. XM_039079459.2 → XP_038935387.1  liprin-alpha-2 isoform X16

    UniProtKB/TrEMBL
    F1M8A4
    Related
    ENSRNOP00000093332.2, ENSRNOT00000119432.2
    Conserved Domains (5) summary
    cd09562
    Location:894 → 964
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:1012 → 1077
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1097 → 1168
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:87 → 471
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:265 → 685
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  20. XM_063263783.1 → XP_063119853.1  liprin-alpha-2 isoform X8

  21. XM_039079480.2 → XP_038935408.1  liprin-alpha-2 isoform X42

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:823 → 893
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:941 → 1006
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1026 → 1097
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 462
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:348 → 614
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  22. XM_039079475.2 → XP_038935403.1  liprin-alpha-2 isoform X36

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:824 → 894
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:948 → 1013
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1033 → 1104
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 462
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:348 → 614
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  23. XM_039079481.2 → XP_038935409.1  liprin-alpha-2 isoform X43

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:821 → 891
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:939 → 1004
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1024 → 1095
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 462
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:348 → 614
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  24. XM_039079477.2 → XP_038935405.1  liprin-alpha-2 isoform X38

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:823 → 893
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:947 → 1012
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1032 → 1103
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 462
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:348 → 614
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  25. XM_039079482.2 → XP_038935410.1  liprin-alpha-2 isoform X44

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:820 → 890
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:938 → 1003
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1023 → 1094
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 462
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:348 → 614
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  26. XM_063263789.1 → XP_063119859.1  liprin-alpha-2 isoform X17

  27. XM_039079470.2 → XP_038935398.1  liprin-alpha-2 isoform X32

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:824 → 894
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:942 → 1007
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1027 → 1098
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 462
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:348 → 614
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  28. XM_039079478.2 → XP_038935406.1  liprin-alpha-2 isoform X40

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:821 → 891
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:945 → 1010
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1030 → 1101
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 462
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:348 → 614
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  29. XM_039079472.2 → XP_038935400.1  liprin-alpha-2 isoform X33

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:823 → 893
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:941 → 1006
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1026 → 1097
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 462
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:348 → 614
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  30. XM_039079479.2 → XP_038935407.1  liprin-alpha-2 isoform X41

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:820 → 890
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:944 → 1009
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1029 → 1100
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 462
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:348 → 614
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  31. XM_063263793.1 → XP_063119863.1  liprin-alpha-2 isoform X20

  32. XM_039079464.2 → XP_038935392.1  liprin-alpha-2 isoform X25

    UniProtKB/TrEMBL
    F1M8A4
    Related
    ENSRNOP00000104793.1, ENSRNOT00000142386.1
    Conserved Domains (5) summary
    cd09562
    Location:824 → 894
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:948 → 1013
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1033 → 1104
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 462
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:348 → 614
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  33. XM_039079473.2 → XP_038935401.1  liprin-alpha-2 isoform X35

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:821 → 891
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:939 → 1004
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1024 → 1095
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 462
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:348 → 614
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  34. XM_039079465.2 → XP_038935393.1  liprin-alpha-2 isoform X26

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:823 → 893
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:947 → 1012
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1032 → 1103
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 462
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:348 → 614
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  35. XM_039079476.2 → XP_038935404.1  liprin-alpha-2 isoform X37

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:820 → 890
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:938 → 1003
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1023 → 1094
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 462
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:348 → 614
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  36. XM_039079467.2 → XP_038935395.1  liprin-alpha-2 isoform X28

    UniProtKB/TrEMBL
    F1M8A4
    Related
    ENSRNOP00000110837.1, ENSRNOT00000174016.1
    Conserved Domains (5) summary
    cd09562
    Location:821 → 891
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:945 → 1010
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1030 → 1101
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 462
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:348 → 614
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  37. XM_039079468.2 → XP_038935396.1  liprin-alpha-2 isoform X29

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:820 → 890
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:944 → 1009
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1029 → 1100
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 462
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:348 → 614
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  38. XM_063263791.1 → XP_063119861.1  liprin-alpha-2 isoform X19

  39. XM_039079461.2 → XP_038935389.1  liprin-alpha-2 isoform X22

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:828 → 898
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:952 → 1017
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1037 → 1108
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 466
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:352 → 618
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  40. XM_039079471.2 → XP_038935399.1  liprin-alpha-2 isoform X31

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:828 → 898
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:952 → 1017
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1037 → 1108
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 466
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:352 → 618
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  41. XM_039079466.2 → XP_038935394.1  liprin-alpha-2 isoform X27

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:828 → 898
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:946 → 1011
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1031 → 1102
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 466
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:352 → 618
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  42. XM_039079463.2 → XP_038935391.1  liprin-alpha-2 isoform X24

    UniProtKB/TrEMBL
    F1M8A4
    Related
    ENSRNOP00000109305.1, ENSRNOT00000139907.1
    Conserved Domains (5) summary
    cd09562
    Location:825 → 895
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:949 → 1014
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1034 → 1105
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 466
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:352 → 618
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  43. XM_039079474.2 → XP_038935402.1  liprin-alpha-2 isoform X34

    UniProtKB/TrEMBL
    F1M8A4
    Related
    ENSRNOP00000005862.6, ENSRNOT00000005862.8
    Conserved Domains (5) summary
    cd09562
    Location:825 → 895
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:949 → 1014
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1034 → 1105
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 466
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:352 → 618
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  44. XM_039079469.2 → XP_038935397.1  liprin-alpha-2 isoform X30

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:825 → 895
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:943 → 1008
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1028 → 1099
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 466
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:352 → 618
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  45. XM_039079462.2 → XP_038935390.1  liprin-alpha-2 isoform X23

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:827 → 897
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:951 → 1016
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:1036 → 1107
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:127 → 466
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:352 → 618
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  46. XM_063263794.1 → XP_063119864.1  liprin-alpha-2 isoform X21

  47. XM_039079483.2 → XP_038935411.1  liprin-alpha-2 isoform X46

    UniProtKB/TrEMBL
    F1M8A4
    Conserved Domains (5) summary
    cd09562
    Location:796 → 866
    SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
    cd09565
    Location:914 → 979
    SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
    cd09568
    Location:999 → 1070
    SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
    COG1196
    Location:94 → 437
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:323 → 589
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  48. XM_063263795.1 → XP_063119865.1  liprin-alpha-2 isoform X39

  49. XM_063263796.1 → XP_063119866.1  liprin-alpha-2 isoform X45

Nucleotide Protein Strain
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