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Mob3a MOB kinase activator 3A [ Rattus norvegicus (Norway rat) ]

Gene ID: 362833, updated on 2-Nov-2024

Summary

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Official Symbol
Mob3aprovided by RGD
Official Full Name
MOB kinase activator 3Aprovided by RGD
Primary source
RGD:1308187
See related
EnsemblRapid:ENSRNOG00000018971 AllianceGenome:RGD:1308187
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Mobkl2a; Mobkl2b
Summary
Predicted to enable protein kinase activator activity. Predicted to be involved in signal transduction. Predicted to be active in cytoplasm and nucleus. Orthologous to human MOB3A (MOB kinase activator 3A). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 149.6), Thymus (RPKM 103.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Mob3a in Genome Data Viewer
Location:
7q11
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (9661185..9678584)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (9010490..9027888)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (11878943..11896226)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479808 Neighboring gene adaptor related protein complex 3 subunit delta 1 Neighboring gene uncharacterized LOC120093774 Neighboring gene IZUMO family member 4 Neighboring gene SUMO-conjugating enzyme UBC9-B-like Neighboring gene MAPK interacting serine/threonine kinase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein kinase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
MOB kinase activator 3A
Names
MOB1, Mps One Binder kinase activator-like 2A
MOB1, Mps One Binder kinase activator-like 2B
mps one binder kinase activator-like 2A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108734.2 → NP_001102204.1  MOB kinase activator 3A

    See identical proteins and their annotated locations for NP_001102204.1

    Status: PROVISIONAL

    Source sequence(s)
    BC168845
    UniProtKB/TrEMBL
    B5DEX8, F7F4P5
    Related
    ENSRNOP00000025634.5, ENSRNOT00000025634.7
    Conserved Domains (1) summary
    pfam03637
    Location:36 → 208
    Mob1_phocein; Mob1/phocein family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    9661185..9678584
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063263743.1 → XP_063119813.1  MOB kinase activator 3A isoform X1

  2. XM_039079395.1 → XP_038935323.1  MOB kinase activator 3A isoform X2

    UniProtKB/TrEMBL
    B5DEX8, F7F4P5
    Conserved Domains (1) summary
    pfam03637
    Location:36 → 208
    Mob1_phocein; Mob1/phocein family

  3. XM_006240963.5 → XP_006241025.1  MOB kinase activator 3A isoform X2

    See identical proteins and their annotated locations for XP_006241025.1

    UniProtKB/TrEMBL
    B5DEX8, F7F4P5
    Conserved Domains (1) summary
    pfam03637
    Location:36 → 208
    Mob1_phocein; Mob1/phocein family
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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