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reb rebuf [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36275, updated on 22-Aug-2024

Summary

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Official Symbol
rebprovided by FlyBase
Official Full Name
rebufprovided by FlyBase
Primary source
FLYBASE:FBgn0033667
Locus tag
Dmel_CG13183
See related
AllianceGenome:FB:FBgn0033667
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG13183; Dmel\CG13183; Reb
Summary
Involved in trachea morphogenesis. Located in apical part of cell and cytoplasm. Is expressed in dorsal epidermis primordium; embryonic epidermis; embryonic hypopharynx; and embryonic/larval dorsal trunk. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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Location:
48C5-48D2; 2-65 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11904323..11912779, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7791828..7800284, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene eukaryotic translation elongation factor 1 alpha 1 Neighboring gene Microcephalin Neighboring gene Zinc/iron regulated transporter-related protein 48C Neighboring gene long non-coding RNA:CR44305 Neighboring gene long non-coding RNA:CR44312

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Deciphering the genetic programme triggering timely and spatially-regulated chitin deposition. Moussian B, et al. PLoS Genet, 2015 Jan. PMID 25617778, Free PMC Article
  2. Structure of the N-terminal domain of the protein Expansion: an 'Expansion' to the Smad MH2 fold. Beich-Frandsen M, et al. Acta Crystallogr D Biol Crystallogr, 2015 Apr. PMID 25849395, Free PMC Article
  3. A dynamic interplay between chitin synthase and the proteins Expansion/Rebuf reveals that chitin polymerisation and translocation are uncoupled in Drosophila. De Giorgio E, et al. PLoS Biol, 2023 Jan. PMID 36689563, Free PMC Article
  4. rebuff regulates apical luminal matrix to control tube size in Drosophila trachea. Chandran RR, et al. Biol Open, 2018 Sep 5. PMID 30185423, Free PMC Article
  5. The novel Smad protein Expansion regulates the receptor tyrosine kinase pathway to control Drosophila tracheal tube size. Iordanou E, et al. Dev Biol, 2014 Sep 1. PMID 24973580, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A dynamic interplay between chitin synthase and the proteins Expansion/Rebuf reveals that chitin polymerisation and translocation are uncoupled in Drosophila.
    Title: A dynamic interplay between chitin synthase and the proteins Expansion/Rebuf reveals that chitin polymerisation and translocation are uncoupled in Drosophila.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in trachea morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in apical part of cell IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
rebuf
Names
CG13183-PA
reb-PA
rebuff

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    11904323..11912779 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136869.3 → NP_610713.2  rebuf [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610713.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z8Q9
    Related
    FBpp0087160
    Conserved Domains (1) summary
    smart00524
    Location:53 → 220
    DWB; Domain B in dwarfin family proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1Z8Q9 A1Z8Q9
Q8SYD6 Q8SYD6

Gene LinkOut

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