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B4galt5 beta-1,4-galactosyltransferase 5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362275, updated on 14-Nov-2024

Summary

Official Symbol
B4galt5provided by RGD
Official Full Name
beta-1,4-galactosyltransferase 5provided by RGD
Primary source
RGD:1310062
See related
EnsemblRapid:ENSRNOG00000008283 AllianceGenome:RGD:1310062
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable N-acetyllactosamine synthase activity and UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity. Predicted to be involved in several processes, including ganglioside biosynthetic process via lactosylceramide; neurogenesis; and positive regulation of embryonic development. Predicted to act upstream of or within poly-N-acetyllactosamine biosynthetic process. Predicted to be located in Golgi cisterna membrane and Golgi membrane. Predicted to be active in Golgi apparatus. Orthologous to human B4GALT5 (beta-1,4-galactosyltransferase 5). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Adrenal (RPKM 153.8), Lung (RPKM 92.7) and 9 other tissues See more
Orthologs
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Genomic context

See B4galt5 in Genome Data Viewer
Location:
3q42
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (176437073..176453001, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (156018056..156033983, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (164039731..164055561, complement)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene prostaglandin I2 synthase Neighboring gene ribosomal protein L38, pseudogene 9 Neighboring gene uncharacterized LOC120101788 Neighboring gene small nucleolar RNA SNORD22

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables N-acetyllactosamine synthase activity ISO
Inferred from Sequence Orthology
more info
 
enables UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in central nervous system myelination ISO
Inferred from Sequence Orthology
more info
 
involved_in central nervous system neuron axonogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in ganglioside biosynthetic process via lactosylceramide ISO
Inferred from Sequence Orthology
more info
 
involved_in glycoprotein biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in glycosylation ISO
Inferred from Sequence Orthology
more info
 
involved_in neuron maturation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within poly-N-acetyllactosamine biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of embryonic development ISO
Inferred from Sequence Orthology
more info
 
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
 
involved_in protein glycosylation ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of protein stability ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
beta-1,4-galactosyltransferase 5
Names
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
NP_001102078.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108608.1NP_001102078.1  beta-1,4-galactosyltransferase 5

    See identical proteins and their annotated locations for NP_001102078.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474005
    UniProtKB/TrEMBL
    A6JXJ4, F1LZL3
    Related
    ENSRNOP00000060927.2, ENSRNOT00000064849.5
    Conserved Domains (1) summary
    pfam13733
    Location:70130
    Glyco_transf_7N; N-terminal region of glycosyl transferase group 7

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    176437073..176453001 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)