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Ankrd13d ankyrin repeat domain 13D [ Rattus norvegicus (Norway rat) ]

Gene ID: 361699, updated on 9-Dec-2024

Summary

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Official Symbol
Ankrd13dprovided by RGD
Official Full Name
ankyrin repeat domain 13Dprovided by RGD
Primary source
RGD:1309156
See related
EnsemblRapid:ENSRNOG00000028247 AllianceGenome:RGD:1309156
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1309156
Summary
Predicted to enable ubiquitin-modified protein reader activity. Predicted to be involved in negative regulation of receptor internalization. Predicted to be located in perinuclear region of cytoplasm and plasma membrane. Predicted to be active in cytoplasm. Orthologous to human ANKRD13D (ankyrin repeat domain 13D). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Brain (RPKM 132.4), Thymus (RPKM 63.4) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ankrd13d in Genome Data Viewer
Location:
1q43
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (210995012..211007430, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (201565712..201577987, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (219520316..219532718, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103691274 Neighboring gene slingshot protein phosphatase 3 Neighboring gene G protein-coupled receptor kinase 2 Neighboring gene lysine demethylase 2A Neighboring gene small nucleolar RNA SNORA32

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The Ankrd 13 family of UIM-bearing proteins regulates EGF receptor endocytosis from the plasma membrane. Tanno H, et al. Mol Biol Cell, 2012 Apr. PMID 22298428, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ubiquitin-modified protein reader activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in negative regulation of receptor internalization ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in late endosome IEA
Inferred from Electronic Annotation
more info
  
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
ankyrin repeat domain-containing protein 13D
Names
ankyrin repeat domain 13 family, member D

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108514.1 → NP_001101984.1  ankyrin repeat domain-containing protein 13D

    See identical proteins and their annotated locations for NP_001101984.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473953
    UniProtKB/TrEMBL
    A6HYX0, D3ZUJ7
    Related
    ENSRNOP00000025641.5, ENSRNOT00000025641.8
    Conserved Domains (3) summary
    sd00045
    Location:39 → 70
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:40 → 93
    Ank_4; Ankyrin repeats (many copies)
    pfam11904
    Location:155 → 469
    GPCR_chapero_1; GPCR-chaperone

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    210995012..211007430 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006230842.5 → XP_006230904.1  ankyrin repeat domain-containing protein 13D isoform X1

    Conserved Domains (1) summary
    pfam11904
    Location:90 → 404
    GPCR_chapero_1; GPCR-chaperone

  2. XM_063268220.1 → XP_063124290.1  ankyrin repeat domain-containing protein 13D isoform X2

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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