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Plac8 placenta associated 8 [ Rattus norvegicus (Norway rat) ]

Gene ID: 360914, updated on 2-Nov-2024

Summary

Symbol
Plac8provided by RGD
Full Name
placenta associated 8provided by RGD
Primary source
RGD:1308102
See related
EnsemblRapid:ENSRNOG00000002217 AllianceGenome:RGD:1308102
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable chromatin binding activity. Predicted to be involved in positive regulation of cold-induced thermogenesis and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including brown fat cell differentiation; defense response to bacterium; and response to cold. Biomarker of glucose intolerance. Orthologous to human PLAC8 (placenta associated 8). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 3060.9), Thymus (RPKM 1116.1) and 3 other tissues See more
Orthologs
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Genomic context

See Plac8 in Genome Data Viewer
Location:
14p22
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (9356950..9378586)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (9052601..9074264)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (10692799..10714556)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene nuclear receptor-binding factor 2-like Neighboring gene uncharacterized LOC134481703 Neighboring gene ubiquitin-conjugating enzyme E2 variant 2-like Neighboring gene COP9 signalosome subunit 4 Neighboring gene uncharacterized LOC102550950

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

General protein information

Preferred Names
placenta-specific gene 8 protein
Names
placenta-specific 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108353.1NP_001101823.1  placenta-specific gene 8 protein

    See identical proteins and their annotated locations for NP_001101823.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474022
    UniProtKB/TrEMBL
    B5DF36, F7EWR1
    Conserved Domains (1) summary
    cl04722
    Location:21105
    PLAC8; PLAC8 family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    9356950..9378586
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063273327.1XP_063129397.1  placenta-specific gene 8 protein isoform X1

    UniProtKB/TrEMBL
    B5DF36
    Related
    ENSRNOP00000003012.6, ENSRNOT00000003012.8