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Csgalnact Chondroitin sulfate N-acetylgalactosaminyltransferase [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36079, updated on 18-Sep-2024

Summary

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Official Symbol
Csgalnactprovided by FlyBase
Official Full Name
Chondroitin sulfate N-acetylgalactosaminyltransferaseprovided by FlyBase
Primary source
FLYBASE:FBgn0033500
Locus tag
Dmel_CG12913
See related
AllianceGenome:FB:FBgn0033500
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG12913; dCSGalNAcT1; Dmel\CG12913
Summary
Predicted to enable glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity and glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. Involved in wound healing. Predicted to be located in Golgi cisterna membrane. Orthologous to human CSGALNACT1 (chondroitin sulfate N-acetylgalactosaminyltransferase 1) and CSGALNACT2 (chondroitin sulfate N-acetylgalactosaminyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See Csgalnact in Genome Data Viewer
Location:
46F8-46F9; 2-62 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10249220..10255495)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (6136725..6143000)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45265 Neighboring gene Histidine decarboxylase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Synaptobrevin Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR30009

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Glycosylation of proteins in plants and invertebrates. Wilson IB. Curr Opin Struct Biol, 2002 Oct. PMID 12464307
  2. Mutations of the withered (whd) gene in Drosophila melanogaster confer hypersensitivity to oxidative stress and are lesions of the carnitine palmitoyltransferase I (CPT I) gene. Strub BR, et al. Genome, 2008 Jun. PMID 18521119
  3. Genetic screen in Drosophila melanogaster uncovers a novel set of genes required for embryonic epithelial repair. Campos I, et al. Genetics, 2010 Jan. PMID 19884309, Free PMC Article
  4. Phenotype-based clustering of glycosylation-related genes by RNAi-mediated gene silencing. Yamamoto-Hino M, et al. Genes Cells, 2015 Jun. PMID 25940448, Free PMC Article
  5. Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach. Pazos Obregón F, et al. BMC Genomics, 2015 Sep 15. PMID 26370122, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables acetylgalactosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in chondroitin sulfate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in wound healing HMP PubMed 
Component Evidence Code Pubs
located_in Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
chondroitin sulfate N-acetylgalactosaminyltransferase
Names
CG12913-PA
CG12913-PB
Csgalnact-PA
Csgalnact-PB
NP_001286277.1
NP_610567.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    10249220..10255495
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299348.1 → NP_001286277.1  chondroitin sulfate N-acetylgalactosaminyltransferase, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286277.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z863
    Conserved Domains (1) summary
    cl11394
    Location:59 → 521
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

  2. NM_136723.3 → NP_610567.1  chondroitin sulfate N-acetylgalactosaminyltransferase, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610567.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z863
    Related
    FBpp0087424
    Conserved Domains (1) summary
    cl11394
    Location:59 → 521
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1Z863 A1Z863

Gene LinkOut

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